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The apparent deglycase activity of DJ-1 results from the conversion of free methylglyoxal present in fast equilibrium with hemithioacetals and hemiaminals.
Andreeva, Anna; Bekkhozhin, Zhanibek; Omertassova, Nuriza; Baizhumanov, Timur; Yeltay, Gaziza; Akhmetali, Mels; Toibazar, Daulet; Utepbergenov, Darkhan.
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  • Andreeva A; Department of Biology, School of Sciences and Humanities, Nazarbayev University, Nur-Sultan 010000, Kazakhstan.
  • Bekkhozhin Z; Department of Chemistry, School of Sciences and Humanities, Nazarbayev University, Nur-Sultan 010000, Kazakhstan.
  • Omertassova N; Department of Biology, School of Sciences and Humanities, Nazarbayev University, Nur-Sultan 010000, Kazakhstan.
  • Baizhumanov T; Department of Chemistry, School of Sciences and Humanities, Nazarbayev University, Nur-Sultan 010000, Kazakhstan.
  • Yeltay G; Department of Biology, School of Sciences and Humanities, Nazarbayev University, Nur-Sultan 010000, Kazakhstan.
  • Akhmetali M; Department of Biology, School of Sciences and Humanities, Nazarbayev University, Nur-Sultan 010000, Kazakhstan.
  • Toibazar D; Department of Biology, School of Sciences and Humanities, Nazarbayev University, Nur-Sultan 010000, Kazakhstan.
  • Utepbergenov D; Department of Chemistry, School of Sciences and Humanities, Nazarbayev University, Nur-Sultan 010000, Kazakhstan. Electronic address: darkhan.utepbergenov@nu.edu.kz.
J Biol Chem ; 294(49): 18863-18872, 2019 12 06.
Article en En | MEDLINE | ID: mdl-31653696
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Proteína Desglicasa DJ-1 Límite: Humans Idioma: En Revista: J Biol Chem Año: 2019 Tipo del documento: Article País de afiliación: Kazajstán Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Proteína Desglicasa DJ-1 Límite: Humans Idioma: En Revista: J Biol Chem Año: 2019 Tipo del documento: Article País de afiliación: Kazajstán Pais de publicación: Estados Unidos