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MYC predetermines the sensitivity of gastrointestinal cancer to antifolate drugs through regulating TYMS transcription.
Liu, Tingting; Han, Yumin; Yu, Chunhong; Ji, Yan; Wang, Changxu; Chen, Xiaomin; Wang, Xiang; Shen, Jiayan; Zhang, Yongfeng; Lang, Jing-Yu.
Afiliación
  • Liu T; The CAS_Key Laboratory of Tissue Microenvironment and Tumor, Institute of Health Sciences, Shanghai Jiao Tong University School of Medicine & Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
  • Han Y; The CAS_Key Laboratory of Tissue Microenvironment and Tumor, Institute of Health Sciences, Shanghai Jiao Tong University School of Medicine & Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
  • Yu C; The CAS_Key Laboratory of Tissue Microenvironment and Tumor, Institute of Health Sciences, Shanghai Jiao Tong University School of Medicine & Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
  • Ji Y; Bioinformatics Core, Institute of Health Sciences, Shanghai Jiao Tong University School of Medicine & Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
  • Wang C; The CAS_Key Laboratory of Tissue Microenvironment and Tumor, Institute of Health Sciences, Shanghai Jiao Tong University School of Medicine & Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
  • Chen X; The CAS_Key Laboratory of Tissue Microenvironment and Tumor, Institute of Health Sciences, Shanghai Jiao Tong University School of Medicine & Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
  • Wang X; The CAS_Key Laboratory of Tissue Microenvironment and Tumor, Institute of Health Sciences, Shanghai Jiao Tong University School of Medicine & Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
  • Shen J; The CAS_Key Laboratory of Tissue Microenvironment and Tumor, Institute of Health Sciences, Shanghai Jiao Tong University School of Medicine & Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
  • Zhang Y; The CAS_Key Laboratory of Tissue Microenvironment and Tumor, Institute of Health Sciences, Shanghai Jiao Tong University School of Medicine & Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
  • Lang JY; The CAS_Key Laboratory of Tissue Microenvironment and Tumor, Institute of Health Sciences, Shanghai Jiao Tong University School of Medicine & Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China. Electronic address: jylang@sibs.ac.cn.
EBioMedicine ; 48: 289-300, 2019 Oct.
Article en En | MEDLINE | ID: mdl-31648989
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Timidilato Sintasa / Resistencia a Medicamentos / Regulación Neoplásica de la Expresión Génica / Genes myc / Antagonistas del Ácido Fólico / Neoplasias Gastrointestinales Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Revista: EBioMedicine Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Timidilato Sintasa / Resistencia a Medicamentos / Regulación Neoplásica de la Expresión Génica / Genes myc / Antagonistas del Ácido Fólico / Neoplasias Gastrointestinales Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Revista: EBioMedicine Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos