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A Rare Case of Multicentric Reticulohistiocytosis with Concurrent Rheumatoid Arthritis.
Behera, Anupama; Devi, Sujata; Guru, Satyabrata; Sethy, Madhusmita.
Afiliación
  • Behera A; Internal Medicine, All India Institute of Medical Sciences, Bhubaneswar, IND.
  • Devi S; Internal Medicine, All India Institute of Medical Sciences, Bhubaneswar, IND.
  • Guru S; Internal Medicine, All India Institute of Medical Sciences, Bhubaneswar, IND.
  • Sethy M; Pathology, All India Institute of Medical Sciences, Bhubaneswar, IND.
Cureus ; 11(8): e5476, 2019 Aug 24.
Article en En | MEDLINE | ID: mdl-31646135
Multicentric reticulohistiocytosis (MRH) is a rare multisystem macrophage disorder of unknown etiology characterized by papulonodular skin and mucosal lesions, rapidly progressive erosive symmetric polyarthritis, and inflammation of internal organs. Most often, it is misdiagnosed as rheumatoid arthritis (RA). Here, we report the case of a 60-year-old woman found to have features of both MRH and RA with positive rheumatoid factor and high titer of anti-cyclic citrullinated peptide antibody in serum. It was confirmed by a histopathology of skin lesions, which showed diffuse histiocytic infiltrate with multinucleated giant cells. She was treated with methotrexate, hydroxychloroquine, corticosteroids, and nonsteroidal anti-inflammatory drugs and bisphosphonate.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cureus Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cureus Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos