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Total corneal refractive power and shape in Down syndrome.
Asgari, Soheila; Mehravaran, Shiva; Fotouhi, Akbar; Makateb, Ali; Hashemi, Hassan.
Afiliación
  • Asgari S; Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran.
  • Mehravaran S; ASCEND Center for Biomedical Research, Morgan State University, Baltimore, MD, USA.
  • Fotouhi A; Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
  • Makateb A; Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran.
  • Hashemi H; Noor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran, Iran.
Eur J Ophthalmol ; 31(1): 69-77, 2021 Jan.
Article en En | MEDLINE | ID: mdl-31635486
PURPOSE: To determine the total corneal refractive power in 1-8 mm corneal zones and the 8 mm Q-value in non-keratoconic patients with Down syndrome and normal subjects aged 10-30 years. METHODS: Right eye data from 203 Down syndrome patients (mean ± standard deviation age: 17.0 ± 4.7 years) and 189 age- and gender-matched normal subjects (17.1 ± 4.5 years) were compared. Main extracted Pentacam indices were total corneal refractive power in steep and flat axes, and mean and difference (corneal astigmatism) total corneal refractive power in 1-8 mm zones. RESULTS: Mean total corneal refractive power in 1-8 mm zones was 45.17-45.74 D and 42.91-43.52 D in Down and normal group, respectively (all p < 0.001). The coefficients of variation of total corneal refractive power from the center to the periphery were similar in the two groups (p = 0.855). None of the mean total corneal refractive powers significantly correlated with age, and all of them were significantly higher in females (p < 0.001). Mean total corneal refractive power-based corneal astigmatism in these zones changed from 1.46 to 1.66 D in Down syndrome patients and 1.64 to 1.99 D in normal group. All corneal astigmatism indices were similar between two groups (all p > 0.05). The prevalence of against the rule and oblique astigmatism in all zones were higher in the Down syndrome group (all p < 0.05). CONCLUSION: Adolescent and young non-keratoconic patients with Down syndrome have a more prolate cornea and a homogeneous keratometry distribution. In this population, females have a steeper cornea.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Refracción Ocular / Astigmatismo / Síndrome de Down / Córnea Tipo de estudio: Risk_factors_studies Límite: Adolescent / Adult / Child / Female / Humans / Male Idioma: En Revista: Eur J Ophthalmol Asunto de la revista: OFTALMOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Refracción Ocular / Astigmatismo / Síndrome de Down / Córnea Tipo de estudio: Risk_factors_studies Límite: Adolescent / Adult / Child / Female / Humans / Male Idioma: En Revista: Eur J Ophthalmol Asunto de la revista: OFTALMOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Estados Unidos