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Physical Condition, Glycemia, Liver Function, and Quality of Life in Liver Transplant Recipients After a 12-Month Supervised Exercise Program.
Totti, Valentina; Tamè, Mariarosa; Burra, Patrizia; Mosconi, Giovanni; Roi, Giulio Sergio; Sella, Gianluigi; Ermolao, Andrea; Ferrarese, Alberto; Sgarzi, Sergio; Savino, Gustavo; Parodi, Giuseppe; Poggioli, Giacomo; Ricchiuti, Alessandro; Di Michele, Rocco; Trerotola, Manuela; Nanni Costa, Alessandro.
Afiliación
  • Totti V; Department of Biomedical & Neuromotor Sciences, University of Bologna, Bologna, Italy; Associazione Nazionale Emodializzati, Dialisi e Trapianto, Milano, Italy.
  • Tamè M; Department of Gastrointestinal Diseases, Gastroenterology Division, Sant'Orsola-Malpighi University-Hospital, Bologna, Italy.
  • Burra P; Multivisceral Transplant Unit, Department of Surgery, Oncology and Gastroenterology, Padua University Hospital, Padua, Italy.
  • Mosconi G; Nephrology and Dialysis, Morgagni-Pierantoni Hospital, Forlì, Italy.
  • Roi GS; Isokinetic Medical Group, Education and Research Department, Bologna, Italy.
  • Sella G; Sports Medicine Unit, Regional Hospital of Ravenna, Ravenna, Italy.
  • Ermolao A; Sports Medicine Unit DIMED, Department of Medicine, University of Padua, Padua Italy.
  • Ferrarese A; Multivisceral Transplant Unit, Department of Surgery, Oncology and Gastroenterology, Padua University Hospital, Padua, Italy.
  • Sgarzi S; Sports Medicine Unit, Regional Hospital of Bologna, Bologna, Italy.
  • Savino G; Sports Medicine Unit, Regional Hospital of Modena, Modena, Italy.
  • Parodi G; Sport Medicine Unit - Exercise Therapy Center, ASL "Città di Torino," Italy.
  • Poggioli G; Sports Medicine Unit, ASST Papa Giovanni XXIII Hospital, Bergamo, Italy.
  • Ricchiuti A; Regional Transplant Center, City of Health and Science Molinette Hospital, Turin, Italy.
  • Di Michele R; Department of Biomedical & Neuromotor Sciences, University of Bologna, Bologna, Italy.
  • Trerotola M; Italian National Transplant Center, Rome, Italy.
  • Nanni Costa A; Italian National Transplant Center, Rome, Italy. Electronic address: lia.bellis@iss.it.
Transplant Proc ; 51(9): 2952-2957, 2019 Nov.
Article en En | MEDLINE | ID: mdl-31607623
BACKGROUND AND AIMS: Despite the excellent long-term outcomes in liver transplant (LT) recipients, several medical complications related to lifestyle still represent an issue. This study examined the effects of a 12-month supervised aerobic and strength training program on the aerobic capacity, muscle strength, metabolic profile, liver function, and quality of life of a cohort of LT recipients. METHODS: LT recipients with stable liver function were assigned to interventional exercise (group A) or usual care (group B). Aerobic capacity, muscle strength, metabolic profile, liver and kidney function, and health-related quality of life were assessed at baseline and after 6 and 12 months. Group A attended supervised training sessions 3 times per week for 12 months. Group B received general recommendations about home-based exercise. RESULTS: Forty patients from 6 Italian LT centers were randomized. Twenty-nine (72.5%, men-to-women ratio 23:6, mean age, 52 ± 8 years) LT recipients completed the study. Baseline characteristics were similar between groups except for body mass index and time from LT. No episode of acute rejection nor increase of transaminases occurred. Maximum workload and body mass index increased in both groups over time, but fasting glucose significantly decreased in group A (94.0 ± 15.0 mg/dL vs 90.0 ± 17.0 mg/dL; P = .037) and increased in controls (95.0 ± 24.0 mg/dL vs 102.0 ± 34.0 mg/dL, P = .04). Upper limb muscle strength increased only in supervised LT recipients. Vitality and general and mental health domains significantly improved after physical exercise. CONCLUSIONS: Supervised combined training was safe and effective in increasing aerobic capacity, muscle strength, and quality of life and in improving glucose metabolism in stable LT recipients.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Calidad de Vida / Aptitud Física / Trasplante de Hígado / Terapia por Ejercicio Tipo de estudio: Clinical_trials Aspecto: Patient_preference Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Transplant Proc Año: 2019 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Calidad de Vida / Aptitud Física / Trasplante de Hígado / Terapia por Ejercicio Tipo de estudio: Clinical_trials Aspecto: Patient_preference Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Transplant Proc Año: 2019 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos