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Recent developments in the management of recurrent Clostridioides difficile infection.
Mendo-Lopez, Rafael; Villafuerte-Gálvez, Javier; White, Nicole; Mahoney, Monica V; Kelly, Ciaran P; Alonso, Carolyn D.
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  • Mendo-Lopez R; Department of Medicine, Division of Gastroenterology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
  • Villafuerte-Gálvez J; Department of Medicine, Division of Gastroenterology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
  • White N; Department of Medicine, Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, MA, USA.
  • Mahoney MV; Department of Pharmacy, Beth Israel Deaconess Medical Center, Boston, MA, USA.
  • Kelly CP; Department of Medicine, Division of Gastroenterology, Beth Israel Deaconess Medical Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.
  • Alonso CD; Department of Medicine, Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA. Electronic address: calonso@bidmc.harvard.edu.
Anaerobe ; 62: 102108, 2020 Apr.
Article en En | MEDLINE | ID: mdl-31606481
Clostridioides (formerly Clostridium) difficile is responsible for a substantial burden of nosocomial infection. Recurrent C. difficile infection (rCDI) remains a concern due to its high morbidity, mortality, and cost. Despite the updated 2017 IDSA C. difficile treatment guidelines, there remains a lack of well-studied preventive control measures and treatment modalities for rCDI. There are ongoing efforts to develop novel therapies, such as new antibiotics with a lesser impact on gut microbiota and more targeted therapies, such as bacteriotherapy. This mini review highlights key rCDI management updates, preventive measures and ongoing research on novel treatment strategies including bacteriotherapy.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Clostridioides difficile / Infecciones por Clostridium Tipo de estudio: Guideline Límite: Humans Idioma: En Revista: Anaerobe Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Clostridioides difficile / Infecciones por Clostridium Tipo de estudio: Guideline Límite: Humans Idioma: En Revista: Anaerobe Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido