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The Influence of Drying Temperatures on the Metabolic Profiles and Antioxidant Activity of Manilkara zapota Leaves.
Hernández-Bolio, Gloria I; Dzul-Romero, Rubí E; Velázquez, María G Maldonado; Cresencio, Pedro Zamora; Hernández-Núñez, Emanuel; Aguirre-Crespo, Francisco J.
Afiliación
  • Hernández-Bolio GI; Marine Resources Department, Center for Research and Advanced Studies -National Polytechnic Institute (CINVESTAV-IPN), Unidad Mérida 97310, Mexico. hboliog@gmail.com.
  • Dzul-Romero RE; Laboratory of Pharmaceutical Biotechnology, Faculty of Biological Chemical Sciences, Autonomous University of Campeche, Campeche 24030, Mexico. rubidr94@gmail.com.
  • Velázquez MGM; Laboratory of Pharmaceutical Biotechnology, Faculty of Biological Chemical Sciences, Autonomous University of Campeche, Campeche 24030, Mexico. mgmaldon@uacam.mx.
  • Cresencio PZ; Center for Historical and Social Research, Autonomous University of Campeche, Campeche 24030, Mexico. pezamora@uacam.mx.
  • Hernández-Núñez E; Marine Resources Department, Center for Research and Advanced Studies -National Polytechnic Institute (CINVESTAV-IPN), Unidad Mérida 97310, Mexico. emanuel.hernandez@cinvestav.mx.
  • Aguirre-Crespo FJ; National Council of Science and Technology (CONACYT), Mexico City 03940, Mexico. emanuel.hernandez@cinvestav.mx.
Metabolites ; 9(10)2019 Oct 06.
Article en En | MEDLINE | ID: mdl-31590430
In the present study, the leaves of Manilkara zapota (L.) P. Royen (Sapotaceae), an evergreen tree recognized for its medicinal properties in Southern Mexico, were used as a model to study the effect of different drying temperatures on its metabolic profile and therefore, its antioxidant potential. For this purpose, a methanol extraction of leaves dried at room temperature (25 °C) or by heat convection (50, 75 and 100 °C) were compared in terms of drying efficiency, yield of extraction, total phenol content, 1H-NMR metabolic profile, and DPPH antioxidant activity. The drying curves enabled the fact to be uncovered that drying efficiency improves with increase of temperature, as does the level of total phenols and antioxidant activity. A metabolomics approach using principal component analysis (PCA) and orthogonal projections to latent structures discriminant analysis (OPLS-DA) of the corresponding 1H-NMR profiles allowed the impact of the drying temperature on their metabolic profile to be documented and also, caffeic acid and epicatechin as main secondary metabolites contributing to the antioxidant activity of M. zapota to be identified.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Metabolites Año: 2019 Tipo del documento: Article País de afiliación: México Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Metabolites Año: 2019 Tipo del documento: Article País de afiliación: México Pais de publicación: Suiza