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Lazertinib in patients with EGFR mutation-positive advanced non-small-cell lung cancer: results from the dose escalation and dose expansion parts of a first-in-human, open-label, multicentre, phase 1-2 study.
Ahn, Myung-Ju; Han, Ji-Youn; Lee, Ki Hyeong; Kim, Sang-We; Kim, Dong-Wan; Lee, Yun-Gyoo; Cho, Eun Kyung; Kim, Joo-Hang; Lee, Gyeong-Won; Lee, Jong-Seok; Min, Young Joo; Kim, Jin-Soo; Lee, Sung Sook; Kim, Hye Ryun; Hong, Min Hee; Ahn, Jin Seok; Sun, Jong-Mu; Kim, Heung Tae; Lee, Dae Ho; Kim, Sohee; Cho, Byoung Chul.
Afiliación
  • Ahn MJ; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
  • Han JY; Center for Lung Cancer, Research Institute and Hospital, National Cancer Center, Goyang, South Korea.
  • Lee KH; Division of Medical Oncology, Department of Medicine, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, South Korea.
  • Kim SW; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
  • Kim DW; Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.
  • Lee YG; Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea.
  • Cho EK; Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, South Korea.
  • Kim JH; CHA Bundang Medical Center, CHA University, Seongnam, South Korea.
  • Lee GW; Division of Hemato-Oncology, Department of Internal Medicine, Gyeongsang National University Hospital, Gyeongsang National University of Medicine, Jinju, South Korea.
  • Lee JS; Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South Korea.
  • Min YJ; Division of Hematology and Oncology, Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, South Korea.
  • Kim JS; Department of Internal Medicine, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, South Korea.
  • Lee SS; Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, South Korea.
  • Kim HR; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, South Korea.
  • Hong MH; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, South Korea.
  • Ahn JS; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
  • Sun JM; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
  • Kim HT; Center for Lung Cancer, Research Institute and Hospital, National Cancer Center, Goyang, South Korea.
  • Lee DH; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
  • Kim S; Yuhan Research Institute, Yuhan Corporation, Yongin, South Korea.
  • Cho BC; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, South Korea. Electronic address: cbc1971@yuhs.ac.
Lancet Oncol ; 20(12): 1681-1690, 2019 12.
Article en En | MEDLINE | ID: mdl-31587882

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirazoles / Pirimidinas / Neoplasias Encefálicas / Morfolinas / Carcinoma de Pulmón de Células no Pequeñas / Inhibidores de Proteínas Quinasas / Antineoplásicos Inmunológicos / Neoplasias Pulmonares / Mutación Tipo de estudio: Clinical_trials / Observational_studies / Prognostic_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Oncol Asunto de la revista: NEOPLASIAS Año: 2019 Tipo del documento: Article País de afiliación: Corea del Sur Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirazoles / Pirimidinas / Neoplasias Encefálicas / Morfolinas / Carcinoma de Pulmón de Células no Pequeñas / Inhibidores de Proteínas Quinasas / Antineoplásicos Inmunológicos / Neoplasias Pulmonares / Mutación Tipo de estudio: Clinical_trials / Observational_studies / Prognostic_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Oncol Asunto de la revista: NEOPLASIAS Año: 2019 Tipo del documento: Article País de afiliación: Corea del Sur Pais de publicación: Reino Unido