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Delivery of mRNA vaccines with heterocyclic lipids increases anti-tumor efficacy by STING-mediated immune cell activation.
Miao, Lei; Li, Linxian; Huang, Yuxuan; Delcassian, Derfogail; Chahal, Jasdave; Han, Jinsong; Shi, Yunhua; Sadtler, Kaitlyn; Gao, Wenting; Lin, Jiaqi; Doloff, Joshua C; Langer, Robert; Anderson, Daniel G.
Afiliación
  • Miao L; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Li L; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Huang Y; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Delcassian D; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Chahal J; Ming Wai Lau Centre for Reparative Medicine, Karolinska Institutet, Hong Kong, China.
  • Han J; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Shi Y; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Sadtler K; Department of Anesthesiology, Boston Children's Hospital, Boston, MA, USA.
  • Gao W; Division of Regenerative Medicine and Cellular Therapy, University of Nottingham, Nottingham, UK.
  • Lin J; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Doloff JC; Ming Wai Lau Centre for Reparative Medicine, Karolinska Institutet, Hong Kong, China.
  • Langer R; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Anderson DG; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Nat Biotechnol ; 37(10): 1174-1185, 2019 10.
Article en En | MEDLINE | ID: mdl-31570898
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vehículos Farmacéuticos / ARN Mensajero / Vacunas contra el Cáncer / Lípidos / Antineoplásicos Límite: Animals / Female / Humans Idioma: En Revista: Nat Biotechnol Asunto de la revista: BIOTECNOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vehículos Farmacéuticos / ARN Mensajero / Vacunas contra el Cáncer / Lípidos / Antineoplásicos Límite: Animals / Female / Humans Idioma: En Revista: Nat Biotechnol Asunto de la revista: BIOTECNOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos