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The stem cell-associated transcription co-factor, ZNF521, interacts with GLI1 and GLI2 and enhances the activity of the Sonic hedgehog pathway.
Scicchitano, Stefania; Giordano, Marco; Lucchino, Valeria; Montalcini, Ylenia; Chiarella, Emanuela; Aloisio, Annamaria; Codispoti, Bruna; Zoppoli, Pietro; Melocchi, Valentina; Bianchi, Fabrizio; De Smaele, Enrico; Mesuraca, Maria; Morrone, Giovanni; Bond, Heather M.
Afiliación
  • Scicchitano S; Laboratory of Molecular Haematopoiesis and Stem Cell Biology, Department of Experimental and Clinical Medicine, University Magna Græcia, 88100, Catanzaro, Italy.
  • Giordano M; Unit of Gynecological Oncology Research, European Institute of Oncology IRCCS, Via G. Ripamonti 435, 20141, Milano, Italy.
  • Lucchino V; Laboratory of Molecular Haematopoiesis and Stem Cell Biology, Department of Experimental and Clinical Medicine, University Magna Græcia, 88100, Catanzaro, Italy.
  • Montalcini Y; German Center for Neurodegenerative Diseases (DZNE), 53127, Bonn, Germany.
  • Chiarella E; Laboratory of Molecular Haematopoiesis and Stem Cell Biology, Department of Experimental and Clinical Medicine, University Magna Græcia, 88100, Catanzaro, Italy.
  • Aloisio A; Laboratory of Molecular Haematopoiesis and Stem Cell Biology, Department of Experimental and Clinical Medicine, University Magna Græcia, 88100, Catanzaro, Italy.
  • Codispoti B; Laboratory of Molecular Haematopoiesis and Stem Cell Biology, Department of Experimental and Clinical Medicine, University Magna Græcia, 88100, Catanzaro, Italy.
  • Zoppoli P; Tecnologica Research Institute-Marrelli Hospital, 88900, Crotone, Italy.
  • Melocchi V; Laboratory of Pre-clinical and Translational Research, IRCCS-CROB, Referral Cancer Center of Basilicata, Rionero in Vulture, Italy.
  • Bianchi F; Fondazione IRCCS - Casa Sollievo della Sofferenza, Laboratory of Cancer Biomarkers, San Giovanni Rotondo, 71013, (FG), Italy.
  • De Smaele E; Fondazione IRCCS - Casa Sollievo della Sofferenza, Laboratory of Cancer Biomarkers, San Giovanni Rotondo, 71013, (FG), Italy.
  • Mesuraca M; Department of Experimental Medicine, University La Sapienza, 00161, Rome, Italy.
  • Morrone G; Laboratory of Molecular Haematopoiesis and Stem Cell Biology, Department of Experimental and Clinical Medicine, University Magna Græcia, 88100, Catanzaro, Italy. mes@unicz.it.
  • Bond HM; Laboratory of Molecular Haematopoiesis and Stem Cell Biology, Department of Experimental and Clinical Medicine, University Magna Græcia, 88100, Catanzaro, Italy.
Cell Death Dis ; 10(10): 715, 2019 09 26.
Article en En | MEDLINE | ID: mdl-31558698

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Nucleares / Transducción de Señal / Neoplasias Cerebelosas / Proteínas de Unión al ADN / Proteínas Hedgehog / Proteína con Dedos de Zinc GLI1 / Proteína Gli2 con Dedos de Zinc / Meduloblastoma Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Cell Death Dis Año: 2019 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Nucleares / Transducción de Señal / Neoplasias Cerebelosas / Proteínas de Unión al ADN / Proteínas Hedgehog / Proteína con Dedos de Zinc GLI1 / Proteína Gli2 con Dedos de Zinc / Meduloblastoma Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Cell Death Dis Año: 2019 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido