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HLA-A, -B, -C, -DRB1 and -DQB1 alleles and haplotypes in 194 Southeast Asia Chinese from Peninsular Malaysia.
Too, Chun-Lai; Tan, Lay-Kim; Heselynn, Hussein; Nor-Shuhaila, Shahril; Eashwary, Mageswaran; Wahinuddin, Sulaiman; Lau, Ing Soo; Gun, Suk Chyn; Mohd-Shahrir, Mohamed-Said; Ainon, Mohd-Mokhtar; Azmillah, Rosman; Muhaini, Othman; Shahnaz, Murad.
Afiliación
  • Too CL; Allergy and Immunology Research Center, Institute for Medical Research, Ministry of Health Malaysia, Kuala Lumpur, Malaysia; Department of Medicine, Division of Rheumatology, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden. Electronic address: toocl@imr.gov.my.
  • Tan LK; Allergy and Immunology Research Center, Institute for Medical Research, Ministry of Health Malaysia, Kuala Lumpur, Malaysia.
  • Heselynn H; Department of Medicine, Putrajaya Hospital, Ministry of Health Malaysia, Putrajaya, Malaysia.
  • Nor-Shuhaila S; Department of Medicine, Putrajaya Hospital, Ministry of Health Malaysia, Putrajaya, Malaysia.
  • Eashwary M; Department of Medicine, Putrajaya Hospital, Ministry of Health Malaysia, Putrajaya, Malaysia.
  • Wahinuddin S; Department of Medicine, Hospital Raja Perempuan Bainun, Ministry of Health Malaysia, Perak, Malaysia; Faculty of Medicine, Universiti Kuala Lumpur Royal College of Medicine Perak, Ipoh, Perak, Malaysia.
  • Lau IS; Department of Medicine, Selayang Hospital, Ministry of Health Malaysia, Selayang, Selangor, Malaysia.
  • Gun SC; Department of Medicine, Hospital Tuanku Ja'afar Seremban, Ministry of Health Malaysia, Seremban, Negeri Sembilan, Malaysia.
  • Mohd-Shahrir MS; Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Center, Kuala Lumpur, Malaysia.
  • Ainon MM; Department of Medicine, Tengku Ampuan Afzan Hospital, Ministry of Health Malaysia, Kuantan, Pahang, Malaysia.
  • Azmillah R; Department of Medicine, Selayang Hospital, Ministry of Health Malaysia, Selayang, Selangor, Malaysia.
  • Muhaini O; Department of Medicine, Taiping Hospital, Ministry of Health Malaysia, Perak, Malaysia.
  • Shahnaz M; Allergy and Immunology Research Center, Institute for Medical Research, Ministry of Health Malaysia, Kuala Lumpur, Malaysia.
Hum Immunol ; 80(11): 906-907, 2019 Nov.
Article en En | MEDLINE | ID: mdl-31558331
A total of 194 Southeast Asia Chinese from Peninsular Malaysia were genotyped for HLA-A, -B, -C -DRB1, and -DQB1 loci using polymerase chain reaction sequence-specific oligonucleotide probe hybridization methods. In this report, the HLA-B, HLA-DRB1 and HLA-DQB1 were in Hardy-Weinberg proportions (HWEP) (p > 0.05). We observed significant deviation from HWEP in HLA-A (p < 0.05) and HLA-C (p < 0.01) loci. This genotype data was available in Allele Frequencies Network Database (AFND) Dos Santos et al. (2016).
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antígenos HLA-A / Antígenos HLA-B / Antígenos HLA-C / Pueblo Asiatico / Cadenas beta de HLA-DQ / Cadenas HLA-DRB1 / Genotipo Tipo de estudio: Clinical_trials Límite: Humans País/Región como asunto: Asia Idioma: En Revista: Hum Immunol Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antígenos HLA-A / Antígenos HLA-B / Antígenos HLA-C / Pueblo Asiatico / Cadenas beta de HLA-DQ / Cadenas HLA-DRB1 / Genotipo Tipo de estudio: Clinical_trials Límite: Humans País/Región como asunto: Asia Idioma: En Revista: Hum Immunol Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos