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Disseminated thymic B-cell lymphoma in a Holstein heifer.
Hishamnuri, Wan N A D; Nakagun, Shotaro; Maezawa, Masaki; Sakaguchi, Kana; Akiyama, Nao; Watanabe, Ken-Ichi; Horiuchi, Noriyuki; Kobayashi, Yoshiyasu; Inokuma, Hisashi.
Afiliación
  • Hishamnuri WNAD; Central Region Veterinary Laboratory, Department of Veterinary Service, Selangor, Malaysia (Hishamunuri).
  • Nakagun S; Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Japan (Hishamunuri, Nakagun, Maezawa, Sakaguchi, Akiyama, Watanabe, Horiuchi, Kobayashi, Inokuma).
  • Maezawa M; United Graduate School of Veterinary Sciences, Gifu University, Gifu, Japan (Nakagun, Maezawa, Horiuchi, Kobayashi, Inokuma).
  • Sakaguchi K; Central Region Veterinary Laboratory, Department of Veterinary Service, Selangor, Malaysia (Hishamunuri).
  • Akiyama N; Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Japan (Hishamunuri, Nakagun, Maezawa, Sakaguchi, Akiyama, Watanabe, Horiuchi, Kobayashi, Inokuma).
  • Watanabe KI; United Graduate School of Veterinary Sciences, Gifu University, Gifu, Japan (Nakagun, Maezawa, Horiuchi, Kobayashi, Inokuma).
  • Horiuchi N; Central Region Veterinary Laboratory, Department of Veterinary Service, Selangor, Malaysia (Hishamunuri).
  • Kobayashi Y; Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Japan (Hishamunuri, Nakagun, Maezawa, Sakaguchi, Akiyama, Watanabe, Horiuchi, Kobayashi, Inokuma).
  • Inokuma H; United Graduate School of Veterinary Sciences, Gifu University, Gifu, Japan (Nakagun, Maezawa, Horiuchi, Kobayashi, Inokuma).
J Vet Diagn Invest ; 31(6): 852-855, 2019 Nov.
Article en En | MEDLINE | ID: mdl-31551023
A 19-mo-old Holstein heifer was inactive and dyspneic. Physical examination revealed wheezing, exophthalmos, a cervical mass, and lymphadenopathy. Cytology of the cervical mass and lymph nodes showed predominantly large atypical lymphocytes. Lactate dehydrogenase and thymidine kinase activities were elevated. Although nested PCR for bovine leukemia virus (BLV) using blood was positive, quantitative PCR showed a low number of provirus copies. Autopsy revealed enlargement of most lymph nodes examined, as well as white masses of various sizes in muscles of the left hindlimb and thoracic and abdominal organs. Histopathology revealed severe infiltration with neoplastic lymphocytes in these organs. The cervical mass was immune-positive for B-cell markers. The final diagnosis was thymic B-cell lymphoma with BLV infection.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias del Timo / Enfermedades de los Bovinos / Linfoma de Células B / Leucosis Bovina Enzoótica Tipo de estudio: Diagnostic_studies Límite: Animals Idioma: En Revista: J Vet Diagn Invest Asunto de la revista: MEDICINA VETERINARIA Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias del Timo / Enfermedades de los Bovinos / Linfoma de Células B / Leucosis Bovina Enzoótica Tipo de estudio: Diagnostic_studies Límite: Animals Idioma: En Revista: J Vet Diagn Invest Asunto de la revista: MEDICINA VETERINARIA Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos