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Correlation of Clinicopathological Characteristics of Breast Carcinoma and Depression.
Ilic, Milena B; Mitrovic, Slobodanka Lj; Vuletic, Milena S; Radivojcevic, Uros M; Janjic, Vladimir S; Stankovic, Vesna D; Vojinovic, Radisa H; Stojadinovic, Dobrivoje S; Radmanovic, Branimir R; Jovanovic, Dalibor V.
Afiliación
  • Ilic MB; Department of Pathology, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia. lena.ilic@medf.kg.ac.rs.
  • Mitrovic SL; Department of Pathology, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia. smitrovic@medf.kg.ac.rs.
  • Vuletic MS; Department of Pathology, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia. milena.vuletic@medf.kg.ac.rs.
  • Radivojcevic UM; Department of Surgery, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia. radivojcevicuros@medf.kg.ac.rs.
  • Janjic VS; Department of Psychiatry, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia. vladadok@medf.kg.ac.rs.
  • Stankovic VD; Department of Pathology, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia. wesna.stankovic@medf.kg.ac.rs.
  • Vojinovic RH; Department of Radiology, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia. rhvojinovic@medf.kg.ac.rs.
  • Stojadinovic DS; Department of Anatomy, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia. dobrivoje.stojadinovic@medf.kg.ac.rs.
  • Radmanovic BR; Department of Psychiatry, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia. biokg2005@medf.kg.ac.rs.
  • Jovanovic DV; Department of Pathology, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia. dalekg84@medf.kg.ac.rs.
Healthcare (Basel) ; 7(3)2019 Sep 12.
Article en En | MEDLINE | ID: mdl-31547382
The prevalence of depression among women with breast cancer (BC) is extremely variable in research studies. The aim of this study was to determine the prevalence of depressive disorder in women suffering from BC as well as to examine its relationship with clinical-pathological and immunophenotypic characteristics of BC. The study included 194 patients with BC who were diagnosed with the disease between 2009 and 2015 in the Clinical Center Kragujevac, Serbia. Pathohistological and immunohistochemical analyses was used on the material obtained after the surgical removal of breast tumors, determining all significant clinical and morphological parameters. The level of depression among the examinees confirmed that the differences in the level of depression between the histological grades were statistically significant. According to the univariate binary logistic regression, the depression of a patient correlates with the category of molecular tumor subtype/Luminal A (p < 0.0005), PR expression (p = 0.050) and lymphatic invasion (p = 0.025). Multivariate binary logistic regression showed that the onset of depression associated with the present molecular subtype of the tumor of a worse prognostic character (p = 0.019). Depression is a common disorder in women with breast cancer. The level of depression is correlates with some of the clinicоmorphological and immunophenotypic characteristics of BC.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Healthcare (Basel) Año: 2019 Tipo del documento: Article Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Healthcare (Basel) Año: 2019 Tipo del documento: Article Pais de publicación: Suiza