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Sulfide, sulfoxide and sulfone bridged acyclic nucleoside phosphonates as inhibitors of the Plasmodium falciparum and human 6-oxopurine phosphoribosyltransferases: Synthesis and evaluation.
Klejch, Tomás; Keough, Dianne T; Chavchich, Marina; Travis, Jye; Skácel, Jan; Pohl, Radek; Janeba, Zlatko; Edstein, Michael D; Avery, Vicky M; Guddat, Luke W; Hocková, Dana.
Afiliación
  • Klejch T; The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nám. 2, CZ-16610, Prague 6, Czech Republic.
  • Keough DT; School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, 4072, Australia.
  • Chavchich M; Department of Drug Evaluation, Australian Defence Force Malaria and Infectious Disease Institute, Enoggera, 4051, Australia.
  • Travis J; School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, 4072, Australia; Department of Drug Evaluation, Australian Defence Force Malaria and Infectious Disease Institute, Enoggera, 4051, Australia.
  • Skácel J; The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nám. 2, CZ-16610, Prague 6, Czech Republic.
  • Pohl R; The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nám. 2, CZ-16610, Prague 6, Czech Republic.
  • Janeba Z; The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nám. 2, CZ-16610, Prague 6, Czech Republic.
  • Edstein MD; Department of Drug Evaluation, Australian Defence Force Malaria and Infectious Disease Institute, Enoggera, 4051, Australia.
  • Avery VM; Discovery Biology, Griffith Institute for Drug Discovery, Griffith University, Nathan, Queensland, 4111, Australia.
  • Guddat LW; School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, 4072, Australia. Electronic address: luke.guddat@uq.edu.au.
  • Hocková D; The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nám. 2, CZ-16610, Prague 6, Czech Republic. Electronic address: hockova@uochb.cas.cz.
Eur J Med Chem ; 183: 111667, 2019 Dec 01.
Article en En | MEDLINE | ID: mdl-31536893
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pentosiltransferasa / Plasmodium falciparum / Sulfuros / Sulfonas / Sulfóxidos / Organofosfonatos / Antimaláricos / Nucleósidos Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2019 Tipo del documento: Article País de afiliación: República Checa Pais de publicación: Francia
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pentosiltransferasa / Plasmodium falciparum / Sulfuros / Sulfonas / Sulfóxidos / Organofosfonatos / Antimaláricos / Nucleósidos Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2019 Tipo del documento: Article País de afiliación: República Checa Pais de publicación: Francia