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Glycogen Synthase Kinase-3 Inhibition Sensitizes Pancreatic Cancer Cells to Chemotherapy by Abrogating the TopBP1/ATR-Mediated DNA Damage Response.
Ding, Li; Madamsetty, Vijay S; Kiers, Spencer; Alekhina, Olga; Ugolkov, Andrey; Dube, John; Zhang, Yu; Zhang, Jin-San; Wang, Enfeng; Dutta, Shamit K; Schmitt, Daniel M; Giles, Francis J; Kozikowski, Alan P; Mazar, Andrew P; Mukhopadhyay, Debabrata; Billadeau, Daniel D.
Afiliación
  • Ding L; The Division of Oncology Research, Schulze Center for Novel Therapeutics, Mayo Clinic, Rochester, Minnesota.
  • Madamsetty VS; Department of Biochemistry and Molecular Biology, Mayo Clinic, Jacksonville, Florida.
  • Kiers S; The Division of Oncology Research, Schulze Center for Novel Therapeutics, Mayo Clinic, Rochester, Minnesota.
  • Alekhina O; The Division of Oncology Research, Schulze Center for Novel Therapeutics, Mayo Clinic, Rochester, Minnesota.
  • Ugolkov A; Actuate Therapeutics Inc., Fort Worth, Texas.
  • Dube J; The Division of Oncology Research, Schulze Center for Novel Therapeutics, Mayo Clinic, Rochester, Minnesota.
  • Zhang Y; The Division of Oncology Research, Schulze Center for Novel Therapeutics, Mayo Clinic, Rochester, Minnesota.
  • Zhang JS; The Division of Oncology Research, Schulze Center for Novel Therapeutics, Mayo Clinic, Rochester, Minnesota.
  • Wang E; Center for Precision Medicine, The First Affiliated Hospital of Wenzhou Medical University, Institute of Life Science, Wenzhou University, Zhejiang, China.
  • Dutta SK; Department of Biochemistry and Molecular Biology, Mayo Clinic, Jacksonville, Florida.
  • Schmitt DM; Department of Biochemistry and Molecular Biology, Mayo Clinic, Jacksonville, Florida.
  • Giles FJ; Actuate Therapeutics Inc., Fort Worth, Texas.
  • Kozikowski AP; Actuate Therapeutics Inc., Fort Worth, Texas.
  • Mazar AP; Starwise Therapeutics LLC, Madison, Wisconsin.
  • Mukhopadhyay D; Monopar Therapeutics Inc., Wilmette, Illinois.
  • Billadeau DD; Department of Biochemistry and Molecular Biology, Mayo Clinic, Jacksonville, Florida.
Clin Cancer Res ; 25(21): 6452-6462, 2019 11 01.
Article en En | MEDLINE | ID: mdl-31533931
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Nucleares / Adenocarcinoma / Proteínas Portadoras / Carcinoma Ductal Pancreático / Proteínas de Unión al ADN / Proteínas de la Ataxia Telangiectasia Mutada / Glucógeno Sintasa Quinasa 3 beta Límite: Animals / Humans Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Nucleares / Adenocarcinoma / Proteínas Portadoras / Carcinoma Ductal Pancreático / Proteínas de Unión al ADN / Proteínas de la Ataxia Telangiectasia Mutada / Glucógeno Sintasa Quinasa 3 beta Límite: Animals / Humans Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos