Dietary Supplementation of Methyl Donor l-Methionine Alters Epigenetic Modification in Type 2 Diabetes.

Navik, Umashanker; Sheth, Vaibhav G; Kabeer, Shaheen Wasil; Tikoo, Kulbhushan

Navik, Umashanker; Sheth, Vaibhav G; Kabeer, Shaheen Wasil; Tikoo, Kulbhushan.

Afiliación

Navik U; Laboratory of Epigenetics and Diseases, Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, S.A.S. Nagar, Mohali, Punjab, 160062, India.
Sheth VG; Laboratory of Epigenetics and Diseases, Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, S.A.S. Nagar, Mohali, Punjab, 160062, India.
Kabeer SW; Laboratory of Epigenetics and Diseases, Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, S.A.S. Nagar, Mohali, Punjab, 160062, India.
Tikoo K; Laboratory of Epigenetics and Diseases, Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, S.A.S. Nagar, Mohali, Punjab, 160062, India.

Mol Nutr Food Res ; 63(23): e1801401, 2019 12.

Article en En | MEDLINE | ID: mdl-31532875

Asunto(s)

Metilación de ADN; Diabetes Mellitus Experimental/metabolismo; Diabetes Mellitus Tipo 2/metabolismo; Metionina/administración & dosificación; Animales; ADN (Citosina-5-)-Metiltransferasa 1/genética; Diabetes Mellitus Tipo 2/genética; Suplementos Dietéticos; Glutatión/metabolismo; Masculino; Metformina/farmacología; Proteínas del Tejido Nervioso/genética; Ratas; Ratas Sprague-Dawley; Sirtuina 1/análisis; Estreptozocina

Palabras clave

AMPK and FOXO1; H3K36me2; l-methionine; one-carbon metabolism; type 2 diabetes mellitus

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Metilación de ADN / Diabetes Mellitus Experimental / Diabetes Mellitus Tipo 2 / Metionina Límite: Animals Idioma: En Revista: Mol Nutr Food Res Asunto de la revista: CIENCIAS DA NUTRICAO Año: 2019 Tipo del documento: Article País de afiliación: India Pais de publicación: Alemania

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