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SDHA gain-of-function engages inflammatory mitochondrial retrograde signaling via KEAP1-Nrf2.
Burgener, Anne-Valérie; Bantug, Glenn R; Meyer, Benedikt J; Higgins, Rebecca; Ghosh, Adhideb; Bignucolo, Olivier; Ma, Eric H; Loeliger, Jordan; Unterstab, Gunhild; Geigges, Marco; Steiner, Rebekah; Enamorado, Michel; Ivanek, Robert; Hunziker, Danielle; Schmidt, Alexander; Müller-Durovic, Bojana; Grählert, Jasmin; Epple, Raja; Dimeloe, Sarah; Lötscher, Jonas; Sauder, Ursula; Ebnöther, Monika; Burger, Bettina; Heijnen, Ingmar; Martínez-Cano, Sarai; Cantoni, Nathan; Brücker, Rolf; Kahlert, Christian R; Sancho, David; Jones, Russell G; Navarini, Alexander; Recher, Mike; Hess, Christoph.
Afiliación
  • Burgener AV; Immunobiology Laboratory, Department of Biomedicine, University and University Hospital of Basel, Basel, Switzerland.
  • Bantug GR; Immunobiology Laboratory, Department of Biomedicine, University and University Hospital of Basel, Basel, Switzerland.
  • Meyer BJ; Cambridge Institute of Therapeutic Immunology & Infectious Disease, Department of Medicine, University of Cambridge, Cambridge, UK.
  • Higgins R; Immunodeficiency Laboratory, Department of Biomedicine, University and University Hospital of Basel, Basel, Switzerland.
  • Ghosh A; Division of Dermatology and Dermatology Laboratory, Department of Biomedicine, University and University Hospital of Basel, Basel, Switzerland.
  • Bignucolo O; Division of Dermatology and Dermatology Laboratory, Department of Biomedicine, University and University Hospital of Basel, Basel, Switzerland.
  • Ma EH; Competence Center for Personalized Medicine University of Zürich/Eidgenössische Technische Hochschule, Zürich, Switzerland.
  • Loeliger J; Department of Pharmacology and Toxicology, University of Lausanne, Lausanne, Switzerland.
  • Unterstab G; Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, MI, USA.
  • Geigges M; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.
  • Steiner R; Department of Physiology, McGill University, Montreal, Quebec, Canada.
  • Enamorado M; Immunobiology Laboratory, Department of Biomedicine, University and University Hospital of Basel, Basel, Switzerland.
  • Ivanek R; Immunobiology Laboratory, Department of Biomedicine, University and University Hospital of Basel, Basel, Switzerland.
  • Hunziker D; Epigenomics Group, D-BSSE, Eidgenössische Technische Hochschule, Basel, Switzerland.
  • Schmidt A; Immunobiology Laboratory, Department of Biomedicine, University and University Hospital of Basel, Basel, Switzerland.
  • Müller-Durovic B; Immunobiology Laboratory, entro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.
  • Grählert J; Mucosal Immunology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Washington DC, USA.
  • Epple R; Bioinformatics Facility, Department of Biomedicine, University and University Hospital of Basel, Basel, Switzerland.
  • Dimeloe S; Immunobiology Laboratory, Department of Biomedicine, University and University Hospital of Basel, Basel, Switzerland.
  • Lötscher J; Proteomics Core Facility, Biozentrum, University of Basel, Basel, Switzerland.
  • Sauder U; Immunobiology Laboratory, Department of Biomedicine, University and University Hospital of Basel, Basel, Switzerland.
  • Ebnöther M; Immunobiology Laboratory, Department of Biomedicine, University and University Hospital of Basel, Basel, Switzerland.
  • Burger B; Immunobiology Laboratory, Department of Biomedicine, University and University Hospital of Basel, Basel, Switzerland.
  • Heijnen I; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.
  • Martínez-Cano S; Immunobiology Laboratory, Department of Biomedicine, University and University Hospital of Basel, Basel, Switzerland.
  • Cantoni N; Electron Microscopy Core Facility, Biozentrum, University of Basel, Basel, Switzerland.
  • Brücker R; Division of Hematology and Oncology, Claraspital, Basel, Switzerland.
  • Kahlert CR; Division of Dermatology and Dermatology Laboratory, Department of Biomedicine, University and University Hospital of Basel, Basel, Switzerland.
  • Sancho D; Division Medical Immunology, Laboratory Medicine, University Hospital Basel, Basel, Switzerland.
  • Jones RG; Immunobiology Laboratory, entro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.
  • Navarini A; Division of Hematology, Cantonal Hospital of Aarau, Aargau, Switzerland.
  • Recher M; Division of Internal Medicine and Rheumatology, Hospital St. Anna, Luzern, Switzerland.
  • Hess C; Division of Infectious Diseases, Children's Hospital of St. Gallen, St. Gallen, Switzerland.
Nat Immunol ; 20(10): 1311-1321, 2019 10.
Article en En | MEDLINE | ID: mdl-31527833

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfocitos B / Complejo II de Transporte de Electrones / Inflamación / Linfocitosis / Mitocondrias / Mutación Tipo de estudio: Observational_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Nat Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfocitos B / Complejo II de Transporte de Electrones / Inflamación / Linfocitosis / Mitocondrias / Mutación Tipo de estudio: Observational_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Nat Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Estados Unidos