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Serum or plasma? An old question looking for new answers.
Plebani, Mario; Banfi, Giuseppe; Bernardini, Sergio; Bondanini, Francesco; Conti, Laura; Dorizzi, Romolo; Ferrara, Fulvio Enrico; Mancini, Rita; Trenti, Tommaso.
Afiliación
  • Plebani M; Dipartimento Strutturale Medicina di Laboratorio, Azienda Ospedale Università di Padova, Padova, Italy.
  • Banfi G; Direttore Scientifico, IRCCS Istituto Ortopedico Galeazzi, Università Vita e Salute San Raffaele, Milan, Italy.
  • Bernardini S; Dipartimento di Medicina Sperimentale, Università degli Studi di Tor Vergata, Rome, Italy.
  • Bondanini F; Unità Operativa Complessa Patologia Clinica Presidio, Ospedaliero Sant'Eugenio/CTO ASL Roma 2, Rome, Italy.
  • Conti L; Patologia Clinica, IRCCS Istituto Nazionale Tumori Regina Elena Roma, Rome, Italy.
  • Dorizzi R; Unità Operativa Patologia Clinica, AUSL della Romagna, Cesena, Italy.
  • Ferrara FE; Direttore Servizio Integrato di Medicina di Laboratorio e Anatomia Patologica, Centro Diagnostico Italiano Spa, Milan, Italy.
  • Mancini R; Laboratorio Unico Metropolitano, AUSL Bologna, Bologna, Italy.
  • Trenti T; Dipartimento di Medicina di Laboratorio e Anatomia Patologica Azienda Ospedaliera Universitaria e USL di Modena, Modena, Italy.
Clin Chem Lab Med ; 58(2): 178-187, 2020 01 28.
Article en En | MEDLINE | ID: mdl-31525152
Serum or plasma? An old question looking for new answers. There is a continual debate on what type of sample a clinical laboratory should use. While serum is still considered the gold standard and remains the required sample for some assays, laboratories must consider turn-around time, which is an important metric for laboratory performance and, more importantly, plays a critical role in patient care. In addition, a body of evidence emphasise the choice of plasma in order to prevent modifications of some analytes due to the coagulation process and related interferences. Advantages and disadvantages of serum and plasma are discussed on the basis of current literature and evidence. In addition, data are provided on the current utilisation of the samples (serum or plasma) in Italy and in other countries. Finally, a rationale for a possible switch from serum to plasma is provided.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plasma / Recolección de Muestras de Sangre / Suero Límite: Humans Idioma: En Revista: Clin Chem Lab Med Asunto de la revista: QUIMICA CLINICA / TECNICAS E PROCEDIMENTOS DE LABORATORIO Año: 2020 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plasma / Recolección de Muestras de Sangre / Suero Límite: Humans Idioma: En Revista: Clin Chem Lab Med Asunto de la revista: QUIMICA CLINICA / TECNICAS E PROCEDIMENTOS DE LABORATORIO Año: 2020 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Alemania