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Cryo-EM structures of lipopolysaccharide transporter LptB2FGC in lipopolysaccharide or AMP-PNP-bound states reveal its transport mechanism.
Tang, Xiaodi; Chang, Shenghai; Luo, Qinghua; Zhang, Zhengyu; Qiao, Wen; Xu, Caihuang; Zhang, Changbin; Niu, Yang; Yang, Wenxian; Wang, Ting; Zhang, Zhibo; Zhu, Xiaofeng; Wei, Xiawei; Dong, Changjiang; Zhang, Xing; Dong, Haohao.
Afiliación
  • Tang X; State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, 610041, Chengdu, China.
  • Chang S; Department of Pathology of Sir Run Run Shaw Hospital, and Department of Biophysics, Zhejiang University School of Medicine, 310058, Hangzhou, Zhejiang, China.
  • Luo Q; Center of Cryo Electron Microscopy, Zhejiang University, 310058, Hangzhou, Zhejiang, China.
  • Zhang Z; State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, 610041, Chengdu, China.
  • Qiao W; Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, School of Pharmaceutical Sciences, Wuhan University, 430071, Wuhan, China.
  • Xu C; State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, 610041, Chengdu, China.
  • Zhang C; Department of Pathology of Sir Run Run Shaw Hospital, and Department of Biophysics, Zhejiang University School of Medicine, 310058, Hangzhou, Zhejiang, China.
  • Niu Y; State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, 610041, Chengdu, China.
  • Yang W; State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, 610041, Chengdu, China.
  • Wang T; State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, 610041, Chengdu, China.
  • Zhang Z; College of Life Science, Sichuan University, 610041, Chengdu, China.
  • Zhu X; State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, 610041, Chengdu, China.
  • Wei X; State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, 610041, Chengdu, China.
  • Dong C; State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, 610041, Chengdu, China.
  • Zhang X; College of Life Science, Sichuan University, 610041, Chengdu, China.
  • Dong H; State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, 610041, Chengdu, China.
Nat Commun ; 10(1): 4175, 2019 09 13.
Article en En | MEDLINE | ID: mdl-31519889
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Bacterianas / Adenilil Imidodifosfato / Lipopolisacáridos / Proteínas de la Membrana Tipo de estudio: Prognostic_studies Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Bacterianas / Adenilil Imidodifosfato / Lipopolisacáridos / Proteínas de la Membrana Tipo de estudio: Prognostic_studies Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido