Dynamics of Circulating Tumor Cells Early After Targeting Therapy to Human <i>EGFR</i>-mutated Lung Cancers and <i>HER2</i> Gene-amplified Gastric Cancers in Mice.

Ito, Akihiro; Nakanishi, Hayao; Yoshimura, Mayumi; Ito, Seiji; Sakao, Yukihiro; Kodera, Yasuhiro; Yatabe, Yasushi; Kaneda, Norio

Dynamics of Circulating Tumor Cells Early After Targeting Therapy to Human EGFR-mutated Lung Cancers and HER2 Gene-amplified Gastric Cancers in Mice.

Ito, Akihiro; Nakanishi, Hayao; Yoshimura, Mayumi; Ito, Seiji; Sakao, Yukihiro; Kodera, Yasuhiro; Yatabe, Yasushi; Kaneda, Norio.

Afiliación

Ito A; Laboratory of Analytical Neurobiology, Faculty of Pharmacy, Meijo University, Nagoya, Japan.
Nakanishi H; Department of Pathology and Molecular Diagnostics, Aichi Cancer Center Hospital, Nagoya, Japan.
Yoshimura M; Department of Pharmacy, Chubu Rousai Hospital, Nagoya, Japan.
Ito S; Department of Pathology and Molecular Diagnostics, Aichi Cancer Center Hospital, Nagoya, Japan hnakanis@aichi-cc.jp.
Sakao Y; Department of Gastroenterological Surgery, Graduate School of Medicine, Nagoya University, Nagoya, Japan.
Kodera Y; Department of Pathology and Molecular Diagnostics, Aichi Cancer Center Hospital, Nagoya, Japan.
Yatabe Y; Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Nagoya, Japan.
Kaneda N; Department of Thoracic Surgery, Faculty of Medical Technologies, Teikyo Medical University, Tokyo, Japan.

Anticancer Res ; 39(9): 4711-4720, 2019 Sep.

Article en En | MEDLINE | ID: mdl-31519570

Asunto(s)

Amplificación de Genes; Mutación; Células Neoplásicas Circulantes/metabolismo; Receptor ErbB-2/genética; Neoplasias Gástricas/genética; Neoplasias Gástricas/patología; Animales; Antineoplásicos/farmacología; Biomarcadores; Biomarcadores de Tumor; Línea Celular Tumoral; Modelos Animales de Enfermedad; Receptores ErbB/genética; Clorhidrato de Erlotinib/farmacología; Xenoinjertos; Humanos; Inmunohistoquímica; Ratones; Células Neoplásicas Circulantes/patología; Neoplasias Gástricas/tratamiento farmacológico

Palabras clave

CTC; automated microfluidic device; cytology; gastric cancer; in vivo dynamics; lung cancer; molecular targeting therapy; preclinical study

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Gástricas / Amplificación de Genes / Receptor ErbB-2 / Mutación / Células Neoplásicas Circulantes Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Anticancer Res Año: 2019 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Grecia

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