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Characterization of the Ontogeny of Hepatic UDP-Glucuronosyltransferase Enzymes Based on Glucuronidation Activity Measured in Human Liver Microsomes.
Badée, Justine; Qiu, Nahong; Collier, Abby C; Takahashi, Ryan H; Forrest, William F; Parrott, Neil; Schmidt, Stephan; Fowler, Stephen.
Afiliación
  • Badée J; Department of Pharmaceutics, Center for Pharmacometrics and Systems Pharmacology, University of Florida at Lake Nona, Orlando, Florida, USA.
  • Qiu N; Pharmaceutical Sciences, Roche Pharma Research and Early Development, Roche Innovation Centre Basel, Basel, Switzerland.
  • Collier AC; Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, British Columbia, Canada.
  • Takahashi RH; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, California, USA.
  • Forrest WF; Department of Bioinformatics and Computational Biology, Genentech, Inc., South San Francisco, California, USA.
  • Parrott N; Pharmaceutical Sciences, Roche Pharma Research and Early Development, Roche Innovation Centre Basel, Basel, Switzerland.
  • Schmidt S; Department of Pharmaceutics, Center for Pharmacometrics and Systems Pharmacology, University of Florida at Lake Nona, Orlando, Florida, USA.
  • Fowler S; Pharmaceutical Sciences, Roche Pharma Research and Early Development, Roche Innovation Centre Basel, Basel, Switzerland.
J Clin Pharmacol ; 59 Suppl 1: S42-S55, 2019 09.
Article en En | MEDLINE | ID: mdl-31502688

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Microsomas Hepáticos / Glucuronosiltransferasa / Hígado Tipo de estudio: Prognostic_studies Límite: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged Idioma: En Revista: J Clin Pharmacol Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Microsomas Hepáticos / Glucuronosiltransferasa / Hígado Tipo de estudio: Prognostic_studies Límite: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged Idioma: En Revista: J Clin Pharmacol Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido