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Anticancer organorhodium and -iridium complexes with low toxicity in vivo but high potency in vitro: DNA damage, reactive oxygen species formation, and haemolytic activity.
Parveen, Shahida; Hanif, Muhammad; Leung, Euphemia; Tong, Kelvin K H; Yang, Annie; Astin, Jonathan; De Zoysa, Gayan H; Steel, Tasha R; Goodman, David; Movassaghi, Sanam; Söhnel, Tilo; Sarojini, Vijayalekshmi; Jamieson, Stephen M F; Hartinger, Christian G.
Afiliación
  • Parveen S; School of Chemical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand. c.hartinger@auckland.ac.nz m.hanif@auckland.ac.nz.
  • Hanif M; School of Chemical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand. c.hartinger@auckland.ac.nz m.hanif@auckland.ac.nz.
  • Leung E; Auckland Cancer Society Research Centre, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Tong KKH; School of Chemical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand. c.hartinger@auckland.ac.nz m.hanif@auckland.ac.nz.
  • Yang A; Department of Molecular Medicine and Pathology, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Astin J; Department of Molecular Medicine and Pathology, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • De Zoysa GH; School of Chemical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand. c.hartinger@auckland.ac.nz m.hanif@auckland.ac.nz.
  • Steel TR; School of Chemical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand. c.hartinger@auckland.ac.nz m.hanif@auckland.ac.nz.
  • Goodman D; School of Chemical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand. c.hartinger@auckland.ac.nz m.hanif@auckland.ac.nz.
  • Movassaghi S; School of Chemical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand. c.hartinger@auckland.ac.nz m.hanif@auckland.ac.nz.
  • Söhnel T; School of Chemical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand. c.hartinger@auckland.ac.nz m.hanif@auckland.ac.nz.
  • Sarojini V; School of Chemical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand. c.hartinger@auckland.ac.nz m.hanif@auckland.ac.nz.
  • Jamieson SMF; Auckland Cancer Society Research Centre, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Hartinger CG; School of Chemical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand. c.hartinger@auckland.ac.nz m.hanif@auckland.ac.nz.
Chem Commun (Camb) ; 55(80): 12016-12019, 2019 Oct 03.
Article en En | MEDLINE | ID: mdl-31498360
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Rodio / Daño del ADN / Especies Reactivas de Oxígeno / Complejos de Coordinación / Iridio / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2019 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Rodio / Daño del ADN / Especies Reactivas de Oxígeno / Complejos de Coordinación / Iridio / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2019 Tipo del documento: Article Pais de publicación: Reino Unido