Nucleic acid-based theranostics in type 1 diabetes.

Dwan, Bennett Francis; Moore, Anna; Wang, Ping

Dwan, Bennett Francis; Moore, Anna; Wang, Ping.

Afiliación

Dwan BF; Precision Health Program, Department of Radiology, College of Human Medicine, Michigan State University, East Lansing, Michigan; College of Natural Science, Michigan State University, East Lansing, Michigan.
Moore A; Precision Health Program, Department of Radiology, College of Human Medicine, Michigan State University, East Lansing, Michigan.
Wang P; Precision Health Program, Department of Radiology, College of Human Medicine, Michigan State University, East Lansing, Michigan. Electronic address: wangpin4@msu.edu.

Transl Res ; 214: 50-61, 2019 12.

Article en En | MEDLINE | ID: mdl-31491371

RESUMEN

Application of RNAi interference for type 1 diabetes (T1D) therapy bears tremendous potential. This review will discuss vehicles for oligonucleotide delivery, imaging modalities used for delivery monitoring, therapeutic targets, and different theranostic strategies that can be applied for T1D treatment.

Asunto(s)

Diabetes Mellitus Tipo 1/terapia; Ácidos Nucleicos/uso terapéutico; Nanomedicina Teranóstica; Rechazo de Injerto/inmunología; Humanos; Islotes Pancreáticos/metabolismo; Terapia Molecular Dirigida

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ácidos Nucleicos / Diabetes Mellitus Tipo 1 / Nanomedicina Teranóstica Límite: Humans Idioma: En Revista: Transl Res Asunto de la revista: MEDICINA / TECNICAS E PROCEDIMENTOS DE LABORATORIO Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos

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