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A 37-year Update on Mortality Patterns in an Expanded Cohort of Vermont Talc Miners and Millers.
Fordyce, Tiffani A; Leonhard, Megan J; Mowat, Fionna S; Moolgavkar, Suresh H.
Afiliación
  • Fordyce TA; Exponent, Inc., Menlo Park, California (Dr Fordyce and Dr Mowat); Exponent, Inc., Bellevue, Washington (Dr Leonhard and Dr Moolgavkar).
J Occup Environ Med ; 61(11): 916-923, 2019 11.
Article en En | MEDLINE | ID: mdl-31490895
OBJECTIVES: The aim of this study was to update a cohort of Vermont talc workers to include 37 additional years of follow-up time. METHODS: Standardized mortality ratios (SMR) and 95% confidence intervals (CIs) were calculated for 70+ causes of death. US population mortality rates were used as reference. RESULTS: All-cause mortality was 30% higher than the US population (SMR 133.4, 95% CI, 119.7 to 148.3). Significant elevations occurred in nonmalignant respiratory disease (NMRD) (SMR 273.0, 95% CI, 210.2 to 348.6) and other nonmalignant respiratory disease (ONMRD) (SMR 413.1, 95% CI, 287.7 to 574.5). ONMRD was elevated across all length of employment categories and a test for linear trend was significant (P = 0.007). CONCLUSIONS: This study provides further evidence that excess deaths among Vermont talc workers are due largely to excess mortality from NMRD; there is no evidence of increased risk of respiratory cancer.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades Respiratorias / Talco / Causas de Muerte / Minería / Neoplasias / Enfermedades Profesionales Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Humans / Male / Middle aged País/Región como asunto: America do norte Idioma: En Revista: J Occup Environ Med Asunto de la revista: MEDICINA OCUPACIONAL / SAUDE AMBIENTAL Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades Respiratorias / Talco / Causas de Muerte / Minería / Neoplasias / Enfermedades Profesionales Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Humans / Male / Middle aged País/Región como asunto: America do norte Idioma: En Revista: J Occup Environ Med Asunto de la revista: MEDICINA OCUPACIONAL / SAUDE AMBIENTAL Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos