[Characteristics of the immunologic response to Mycoplasma pneumoniae as a polyclonal lymphocyte activator]. / Osobennost' immunologicheskogo otveta na Mycoplasma pneumoniae kak na poliklonal'nyi aktivator limfotsitov.
Zh Mikrobiol Epidemiol Immunobiol
; (8): 108-11, 1988 Aug.
Article
en Ru
| MEDLINE
| ID: mdl-3143202
M. pneumoniae, used as mitogen, was shown to initiate the synthesis of antibodies to salmonellae in the culture of lymphocytes obtained from healthy donors as actively as lectins and Staphylococcus aureus protein A. In these experiments IgG antibodies were mainly synthesized. The serological study of a group of persons (333 subjects) for 2.5 years revealed that seroconversion to M. pneumoniae and simultaneously to viruses occurred in 78% of cases. In more than a half of the cases a rise in the titers of antibodies to M. pneumoniae and simultaneously to salmonellae was found to occur with no cases of salmonellosis being registered. The results of this study make it possible to come to the conclusion that M. pneumoniae is a polyclonal activator of antibody-producing cells in vitro and, probably, in vivo.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Activación de Linfocitos
/
Mycoplasma pneumoniae
Límite:
Adolescent
/
Adult
/
Humans
Idioma:
Ru
Revista:
Zh Mikrobiol Epidemiol Immunobiol
Año:
1988
Tipo del documento:
Article
Pais de publicación:
Rusia