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AAV-ie enables safe and efficient gene transfer to inner ear cells.
Tan, Fangzhi; Chu, Cenfeng; Qi, Jieyu; Li, Wenyan; You, Dan; Li, Ke; Chen, Xin; Zhao, Weidong; Cheng, Cheng; Liu, Xiaoyi; Qiao, Yunbo; Su, Bing; He, Shuijin; Zhong, Chao; Li, Huawei; Chai, Renjie; Zhong, Guisheng.
Afiliación
  • Tan F; iHuman Institute, ShanghaiTech University, 201210, Shanghai, China. tanfzh@shanghaitech.edu.cn.
  • Chu C; iHuman Institute, ShanghaiTech University, 201210, Shanghai, China.
  • Qi J; School of Life Science and Technology, ShanghaiTech University, 201210, Shanghai, China.
  • Li W; University of the Chinese Academy of Sciences, 100049, Beijing, China.
  • You D; MOE Key Laboratory for Developmental Genes and Human Disease, Institute of Life Sciences, Jiangsu Province High-Tech Key Laboratory for Bio-Medical Research, Southeast University, 210096, Nanjing, China.
  • Li K; Co-innovation Center of Neuroregeneration, Jiangsu Key Laboratory of Neuroregeneration, Nantong University, Nantong, China.
  • Chen X; ENT Institute and Otorhinolaryngology Department of Affiliated Eye and ENT Hospital, Key Laboratory of Hearing Medicine of NHFPC, Shanghai Engineering Research Centre of Cochlear Implant, State Key Laboratory of Medical Neurobiology, Fudan University, 200031, Shanghai, China.
  • Zhao W; ENT Institute and Otorhinolaryngology Department of Affiliated Eye and ENT Hospital, Key Laboratory of Hearing Medicine of NHFPC, Shanghai Engineering Research Centre of Cochlear Implant, State Key Laboratory of Medical Neurobiology, Fudan University, 200031, Shanghai, China.
  • Cheng C; University of the Chinese Academy of Sciences, 100049, Beijing, China.
  • Liu X; School of Physical Science and Technology, ShanghaiTech University, 201210, Shanghai, China.
  • Qiao Y; Shanghai Institute of Ceramics, Chinese Academy of Sciences, 200050, Shanghai, China.
  • Su B; School of Life Science and Technology, ShanghaiTech University, 201210, Shanghai, China.
  • He S; University of the Chinese Academy of Sciences, 100049, Beijing, China.
  • Zhong C; ENT Institute and Otorhinolaryngology Department of Affiliated Eye and ENT Hospital, Key Laboratory of Hearing Medicine of NHFPC, Shanghai Engineering Research Centre of Cochlear Implant, State Key Laboratory of Medical Neurobiology, Fudan University, 200031, Shanghai, China.
  • Li H; Department of Otolaryngology Head and Neck Surgery, Affiliated Drum Tower Hospital of Nanjing University Medical School, Jiangsu Provincial Key Medical Discipline (Laboratory), No. 321 Zhongshan Road, 210008, Nanjing, China.
  • Chai R; Research Institute of Otolaryngology, No. 321 Zhongshan Road, 210008, Nanjing, China.
  • Zhong G; iHuman Institute, ShanghaiTech University, 201210, Shanghai, China.
Nat Commun ; 10(1): 3733, 2019 08 19.
Article en En | MEDLINE | ID: mdl-31427575

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Terapia Genética / Dependovirus / Factores de Transcripción con Motivo Hélice-Asa-Hélice Básico / Células Ciliadas Auditivas Internas / Pérdida Auditiva Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Terapia Genética / Dependovirus / Factores de Transcripción con Motivo Hélice-Asa-Hélice Básico / Células Ciliadas Auditivas Internas / Pérdida Auditiva Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido