Nomenclature clarification: synovial fibroblasts and synovial mesenchymal stem cells.
Stem Cell Res Ther
; 10(1): 260, 2019 08 19.
Article
en En
| MEDLINE
| ID: mdl-31426847
Synovial-derived cells, found in the synovial membrane of human joints, were obtained by digestion of the synovial membrane and were subsequently expanded in vitro. The identity of synovial-derived cells has long been a topic of debate. The terms "type B synoviocytes," "fibroblast-like synoviocytes (FLS)," "synovium-derived mesenchymal stem cells (MSCs)," and "synovial fibroblasts (SF)" appeared in different articles related to human synovial-derived cells in various disease models, yet they seemed to be describing the same cell type. However, to date, there is no clear standard to distinguish these terms; thus, the hypothesis that they represent the same cell type is currently inconclusive. Therefore, this review aims to clarify the similarities and differences between these terms and to diffuse the chaotic nomenclature of synovial-derived cells.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Membrana Sinovial
/
Células Madre Mesenquimatosas
/
Fibroblastos
/
Terminología como Asunto
Límite:
Humans
Idioma:
En
Revista:
Stem Cell Res Ther
Año:
2019
Tipo del documento:
Article
País de afiliación:
China
Pais de publicación:
Reino Unido