Long non-coding RNA HOTTIP promotes hypoxia-induced glycolysis through targeting miR-615-3p/HMGB3 axis in non-small cell lung cancer cells.

Shi, Jiang; Wang, Huan; Feng, Wanlu; Huang, Siyuan; An, Jinlu; Qiu, Yajuan; Wu, Kai

Shi, Jiang; Wang, Huan; Feng, Wanlu; Huang, Siyuan; An, Jinlu; Qiu, Yajuan; Wu, Kai.

Afiliación

Shi J; Department of Respiratory, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Erqi District, 450052, Zhengzhou, Henan, China.
Wang H; Department of Respiratory, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Erqi District, 450052, Zhengzhou, Henan, China.
Feng W; Department of Respiratory, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Erqi District, 450052, Zhengzhou, Henan, China.
Huang S; Department of Oncology, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Erqi District, 450052, Zhengzhou, Henan, China.
An J; Department of Respiratory, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Erqi District, 450052, Zhengzhou, Henan, China.
Qiu Y; Department of Respiratory, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Erqi District, 450052, Zhengzhou, Henan, China.
Wu K; Department of Thoracic Surgery, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Erqi District, 450052, Zhengzhou, Henan, China. Electronic address: fccwuk@zzu.edu.cn.

Eur J Pharmacol ; 862: 172615, 2019 Nov 05.

Article en En | MEDLINE | ID: mdl-31422060

Asunto(s)

Carcinoma de Pulmón de Células no Pequeñas/genética; Proteína HMGB3/genética; Neoplasias Pulmonares/genética; MicroARNs/metabolismo; ARN Largo no Codificante/metabolismo; Células A549; Carcinoma de Pulmón de Células no Pequeñas/patología; Hipoxia de la Célula/genética; Regulación hacia Abajo; Regulación Neoplásica de la Expresión Génica; Glucosa/metabolismo; Glucólisis/genética; Proteína HMGB3/metabolismo; Humanos; Pulmón; Neoplasias Pulmonares/patología; MicroARNs/genética; Regulación hacia Arriba

Palabras clave

Glycolysis; HMGB3; HOXA transcript at the distal tip (HOTTIP); Hypoxia; NSCLC; miR-615-3p

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma de Pulmón de Células no Pequeñas / Proteína HMGB3 / MicroARNs / ARN Largo no Codificante / Neoplasias Pulmonares Límite: Humans Idioma: En Revista: Eur J Pharmacol Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos

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