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Environmental determinants associated with acute otitis media in children: a longitudinal study.
van Ingen, Gijs; le Clercq, Carlijn M P; Touw, Carolina E; Duijts, Liebeth; Moll, Henriette A; Jaddoe, Vincent W V; Raat, Hein; Baatenburg de Jong, Robert J; van der Schroeff, Marc P.
Afiliación
  • van Ingen G; Department of Otolaryngology - Head and Neck Surgery, Erasmus MC, Rotterdam, Netherlands. g.vaningen@erasmusmc.nl.
  • le Clercq CMP; The Generation R Study Group, Erasmus MC, Rotterdam, Netherlands. g.vaningen@erasmusmc.nl.
  • Touw CE; Department of Otolaryngology - Head and Neck Surgery, Erasmus MC, Rotterdam, Netherlands.
  • Duijts L; The Generation R Study Group, Erasmus MC, Rotterdam, Netherlands.
  • Moll HA; Department of Otolaryngology - Head and Neck Surgery, Erasmus MC, Rotterdam, Netherlands.
  • Jaddoe VWV; The Generation R Study Group, Erasmus MC, Rotterdam, Netherlands.
  • Raat H; Department of Pediatrics, Erasmus MC, Rotterdam, Netherlands.
  • Baatenburg de Jong RJ; The Generation R Study Group, Erasmus MC, Rotterdam, Netherlands.
  • van der Schroeff MP; Department of Pediatrics, Erasmus MC, Rotterdam, Netherlands.
Pediatr Res ; 87(1): 163-168, 2020 01.
Article en En | MEDLINE | ID: mdl-31421634
BACKGROUND: Acute otitis media (AOM) is a common pediatric disease and frequent reason for antibiotic treatment. We aimed to identify environmental and host factors associated with AOM and assess which determinants were associated with AOM at specific ages. METHODS: This study among 7863 children was embedded in the Generation R Study: a population-based prospective cohort study from fetal life onwards. Data on outcome and possible determinants were collected using questionnaires until 6 years. We used generalized estimating equation models to examine associations with AOM with longitudinal odds at different ages, considering correlations between repeated measurements. RESULTS: Male gender increased odds of AOM in children at 2, 3, and 4 years but not at other ages. Postnatal household smoking, presence of siblings, and pet birds increased odds of AOM. Breastfeeding decreased AOM odds, most notably in the first 2 months of life. No association was found for season of birth, maternal age, ethnicity, aberrant birth weight for gestational age, prenatal smoking, furry pets, and daycare attendance. CONCLUSIONS: Risk of childhood AOM varies with age. Significant association with AOM was found for gender and breastfeeding at specific ages and for household smoking, presence of siblings, and pet birds at all the studied ages.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Otitis Media / Ambiente / Exposición a Riesgos Ambientales Tipo de estudio: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Child / Child, preschool / Female / Humans / Infant / Male / Newborn País/Región como asunto: Europa Idioma: En Revista: Pediatr Res Año: 2020 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Otitis Media / Ambiente / Exposición a Riesgos Ambientales Tipo de estudio: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Child / Child, preschool / Female / Humans / Infant / Male / Newborn País/Región como asunto: Europa Idioma: En Revista: Pediatr Res Año: 2020 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Estados Unidos