Your browser doesn't support javascript.
loading
Cardiovascular ultrashort echo time to map fibrosis-promises and challenges.
Schuijf, Joanne D; Ambale-Venkatesh, Bharath; Kassai, Yoshimori; Kato, Yoko; Kasuboski, Larry; Ota, Hideki; Caruthers, Shelton D; Lima, João Ac.
Afiliación
  • Schuijf JD; Global RDC, Canon Medical Systems Europe BV, Zoetermeer, The Netherlands.
  • Ambale-Venkatesh B; Department of Radiology, Johns Hopkins Hospital and School of Medicine, Baltimore, MD, US.
  • Kassai Y; CT-MR Solution Planning Department, CT-MR Division, Canon Medical Systems, Otawara, Japan.
  • Kato Y; Department of Cardiology, Johns Hopkins Hospital and School of Medicine, Baltimore, MD, USA.
  • Kasuboski L; Canon Medical Research Institute, Cleveland, OH, USA.
  • Ota H; Department of Diagnostic Radiology, Tohoku University Graduate School of Medicine, Miyagi, Japan.
  • Caruthers SD; Canon Medical Research Institute, Cleveland, OH, USA.
  • Lima JA; Department of Cardiology, Johns Hopkins Hospital and School of Medicine, Baltimore, MD, USA.
Br J Radiol ; 92(1103): 20190465, 2019 Nov.
Article en En | MEDLINE | ID: mdl-31356106
Increased collagen, or fibrosis, is an important marker of disease and may improve identification of patients at risk. In addition, fibrosis imaging may play an increasing role in guiding therapy and monitoring its effectiveness. MRI is the most frequently used modality to detect, visualize and quantify fibrosis non-invasively. However, standard MRI techniques used to phenotype cardiac fibrosis such as delayed enhancement and extracellular volume determination by T1 mapping, require the administration of gadolinium-based contrast and are particularly difficult to use in patients with cardiac devices such as pacemakers and automatic defibrillators. Therefore, such methods are limited in the serial evaluation of cardiovascular fibrosis as part of chronic disease monitoring. A method to directly measure collagen amount could be of great clinical benefit. In the current review we will discuss the potential of a novel MR technique, ultrashort echo time (UTE) MR, for fibrosis imaging. Although UTE imaging is successfully applied in other body areas such as musculoskeletal applications, there is very limited experience so far in the heart. We will review the established methods and currently available literature, discuss the technical considerations and challenges, show preliminary in vivo images and provide a future outlook on potential applications of cardiovascular UTE.
Asunto(s)
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sistema Cardiovascular / Angiografía por Resonancia Magnética Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Br J Radiol Año: 2019 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sistema Cardiovascular / Angiografía por Resonancia Magnética Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Br J Radiol Año: 2019 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Reino Unido