Perioperative anesthetic management of patients with malignant pleural mesothelioma undergoing cytoreductive surgery and intraoperative chemotherapy. / Manejo anestésico perioperatorio de pacientes con mesotelioma maligno pleural intervenidos mediante cirugía citorreductora y quimioterapia intratorácica.
Rev Esp Anestesiol Reanim (Engl Ed)
; 67(1): 15-19, 2020 Jan.
Article
en En, Es
| MEDLINE
| ID: mdl-31353039
INTRODUCTION: Cytoreductive surgery with hyperthermic intraoperative chemotherapy (HITHOC) is a therapeutic option for treatment of malignant pleural mesothelioma. Anesthetic management might be challenging. PATIENTS AND METHODS: A descriptive analysis of a case series is presented. Seven patients with malignant pleural mesothelioma diagnostic undergoing HITHOC surgery were studied. Combined general and epidural anesthesia were administered. An intensive hemodynamic monitorization was implemented. Data regarding perioperative course was analyzed. RESULTS: Between May 2015 and October 2018 7patients underwent HITHOC procedure. Blood transfusions were administered in all patients, and 5of the 7patients required vasoactive drug administration. Extubation at the end of the procedure was able in 6of the 7patients. The median length of stay in ICU was 4 days, and 29 days for the whole hospitalary stay. No significant postoperative pain was observed. CONCLUSIONS: HITHOC surgery is a complex procedure in which several hemodynamic changes occur. An intensive intraoperative monitorization was useful for controlling complications.
Palabras clave
Analgesia; Anestesia; Anestesia general; Anestesia intravenosa; Anesthesia; Chemotherapy; Cirugía oncológica; Cirugía torácica; Cuidados perioperatorios; General anesthesia; Hipertermia inducida; Induced hyperthermia; Intravenous anesthesia; Mesotelioma; Mesothelioma; Perioperative care; Pleura; Quimioterapia; Surgical oncology; Thoracic surgery
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias Pleurales
/
Mesotelioma Maligno
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Hipertermia Inducida
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Anestesia Epidural
/
Anestesia General
Tipo de estudio:
Observational_studies
Límite:
Aged
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
/
Es
Revista:
Rev Esp Anestesiol Reanim (Engl Ed)
Año:
2020
Tipo del documento:
Article
Pais de publicación:
España