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Methyl jasmonate abrogates rotenone-induced parkinsonian-like symptoms through inhibition of oxidative stress, release of pro-inflammatory cytokines, and down-regulation of immnopositive cells of NF-κB and α-synuclein expressions in mice.
Alabi, Akinyinka O; Ajayi, Abayomi M; Ben-Azu, Benneth; Bakre, Adewale G; Umukoro, Solomon.
Afiliación
  • Alabi AO; Department of Pharmacology and Therapeutics, Faculty of Basic Medical Sciences, Olabisi Onabanjo University, Ago-Iwoye, Nigeria; Neuropharmacology Unit, Department of Pharmacology and Therapeutics, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
  • Ajayi AM; Neuropharmacology Unit, Department of Pharmacology and Therapeutics, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
  • Ben-Azu B; Neuropharmacology Unit, Department of Pharmacology and Therapeutics, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria; Department of Pharmacology, Faculty of Basic Medical Sciences, PAMO University of Medical Sciences, Port Harcourt, Rivers State, Nigeria
  • Bakre AG; Neuropharmacology Unit, Department of Pharmacology and Therapeutics, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
  • Umukoro S; Neuropharmacology Unit, Department of Pharmacology and Therapeutics, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria. Electronic address: umusolo@yahoo.com.
Neurotoxicology ; 74: 172-183, 2019 09.
Article en En | MEDLINE | ID: mdl-31336111
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Parkinson Secundaria / Rotenona / Desacopladores / Antiinflamatorios no Esteroideos / Citocinas / FN-kappa B / Estrés Oxidativo / Ciclopentanos / Alfa-Sinucleína / Oxilipinas Tipo de estudio: Diagnostic_studies Límite: Animals Idioma: En Revista: Neurotoxicology Año: 2019 Tipo del documento: Article País de afiliación: Nigeria Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Parkinson Secundaria / Rotenona / Desacopladores / Antiinflamatorios no Esteroideos / Citocinas / FN-kappa B / Estrés Oxidativo / Ciclopentanos / Alfa-Sinucleína / Oxilipinas Tipo de estudio: Diagnostic_studies Límite: Animals Idioma: En Revista: Neurotoxicology Año: 2019 Tipo del documento: Article País de afiliación: Nigeria Pais de publicación: Países Bajos