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A pollution gradient contributes to the taxonomic, functional, and resistome diversity of microbial communities in marine sediments.
Chen, Jiarui; McIlroy, Shelby E; Archana, Anand; Baker, David M; Panagiotou, Gianni.
Afiliación
  • Chen J; Systems Biology & Bioinformatics Group, School of Biological Sciences, Faculty of Science, The University of Hong Kong, Hong Kong SAR, China.
  • McIlroy SE; Swire Institute of Marine Science, The University of Hong Kong, Hong Kong SAR, China.
  • Archana A; School of Biological Sciences, Faculty of Science, The University of Hong Kong, Kadoorie Biological Sciences Building, Pok Fu Lam Road, Hong Kong SAR, China.
  • Baker DM; Swire Institute of Marine Science, The University of Hong Kong, Hong Kong SAR, China. dmbaker@hku.hk.
  • Panagiotou G; School of Biological Sciences, Faculty of Science, The University of Hong Kong, Kadoorie Biological Sciences Building, Pok Fu Lam Road, Hong Kong SAR, China. dmbaker@hku.hk.
Microbiome ; 7(1): 104, 2019 07 15.
Article en En | MEDLINE | ID: mdl-31307536
BACKGROUND: Coastal marine environments are one of the most productive ecosystems on Earth. However, anthropogenic impacts exert significant pressure on coastal marine biodiversity, contributing to functional shifts in microbial communities and human health risk factors. However, relatively little is known about the impact of eutrophication-human-derived nutrient pollution-on the marine microbial biosphere. RESULTS: Here, we tested the hypothesis that benthic microbial diversity and function varies along a pollution gradient, with a focus on human pathogens and antibiotic resistance genes. Comprehensive metagenomic analysis including taxonomic investigation, functional detection, and ARG annotation revealed that zinc, lead, total volatile solids, and ammonia nitrogen were correlated with microbial diversity and function. We propose several microbes, including Planctomycetes and sulfate-reducing microbes as candidates to reflect pollution concentration. Annotation of antibiotic resistance genes showed that the highest abundance of efflux pumps was found at the most polluted site, corroborating the relationship between pollution and human health risk factors. This result suggests that sediments at polluted sites harbor microbes with a higher capacity to reduce intracellular levels of antibiotics, heavy metals, or other environmental contaminants. CONCLUSIONS: Our findings suggest a correlation between pollution and the marine sediment microbiome and provide insight into the role of high-turnover microbial communities as well as potential pathogenic organisms as real-time indicators of water quality, with implications for human health and demonstrate the inner functional shifts contributed by the microcommunities.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bacterias / Farmacorresistencia Microbiana / Sedimentos Geológicos / Contaminación Ambiental / Metagenoma / Microbiota Tipo de estudio: Risk_factors_studies Aspecto: Determinantes_sociais_saude País/Región como asunto: Asia Idioma: En Revista: Microbiome Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bacterias / Farmacorresistencia Microbiana / Sedimentos Geológicos / Contaminación Ambiental / Metagenoma / Microbiota Tipo de estudio: Risk_factors_studies Aspecto: Determinantes_sociais_saude País/Región como asunto: Asia Idioma: En Revista: Microbiome Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido