Modification of lactoferrin by peroxynitrite reduces its antibacterial activity and changes protein structure.

Alhalwani, Amani Y; Davey, Rachel L; Kaul, Navneeta; Barbee, Scott A; Alex Huffman, J

Alhalwani, Amani Y; Davey, Rachel L; Kaul, Navneeta; Barbee, Scott A; Alex Huffman, J.

Afiliación

Alhalwani AY; Department of Chemistry and Biochemistry, University of Denver, Denver, Colorado.
Davey RL; Department of Chemistry and Biochemistry, University of Denver, Denver, Colorado.
Kaul N; Department of Biological Sciences, University of Denver, Denver, Colorado.
Barbee SA; Department of Biological Sciences, University of Denver, Denver, Colorado.
Alex Huffman J; Department of Chemistry and Biochemistry, University of Denver, Denver, Colorado.

Proteins ; 88(1): 166-174, 2020 01.

Article en En | MEDLINE | ID: mdl-31295370

Asunto(s)

Antibacterianos/metabolismo; Lactoferrina/metabolismo; Ácido Peroxinitroso/metabolismo; Secuencia de Aminoácidos; Antibacterianos/química; Humanos; Hierro/metabolismo; Lactoferrina/química; Unión Proteica; Procesamiento Proteico-Postraduccional; Estructura Secundaria de Proteína; Desplegamiento Proteico

Palabras clave

antibiotic activity; iron-binding; lactotransferrin; nitration; post-translational modification; protein structure; tyrosine

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ácido Peroxinitroso / Lactoferrina / Antibacterianos Límite: Humans Idioma: En Revista: Proteins Asunto de la revista: BIOQUIMICA Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google