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Microbial Infections as a Trigger for Acute-on-Chronic Liver Failure: A Review.
Cai, Qun; Liu, Wei; Zhu, Mingyan; Sheng, Jifang.
Afiliación
  • Cai Q; Department of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China (mainland).
  • Liu W; Hangzhou Mutai Nursing Hospital, Hangzhou, Zhejiang, China (mainland).
  • Zhu M; Department of Infectious Disease, The Affiliated Chaohu Hospital of Anhui Medical University, Chaohu, Anhui, China (mainland).
  • Sheng J; Department of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China (mainland).
Med Sci Monit ; 25: 4773-4783, 2019 Jun 27.
Article en En | MEDLINE | ID: mdl-31282874
ABSTRACT Microbial infection is an important cause of acute-on-chronic liver failure (ACLF), which is a syndrome that results in multiple organ dysfunction or failure and is accompanied by an increased short-term risk of mortality. Early detection and treatment of microbial infection can effectively reduce the mortality of patients with ACLF. However, antimicrobial resistance has recently increased due to the increased use of antimicrobial agents. Therefore, it is important to choose appropriate antibiotics and antifungal agents for early prevention or treatment of patients with microbial infection and ACLF to reduce the occurrence of drug resistance and to reduce patient mortality. This review summarizes the current status in the understanding of the epidemiology, pathogenesis, early diagnosis, treatment, and strategies for prevention of microbial infection in patients with ACLF.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Insuficiencia Hepática Crónica Agudizada Tipo de estudio: Diagnostic_studies / Etiology_studies / Risk_factors_studies / Screening_studies Límite: Humans Idioma: En Revista: Med Sci Monit Asunto de la revista: MEDICINA Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Insuficiencia Hepática Crónica Agudizada Tipo de estudio: Diagnostic_studies / Etiology_studies / Risk_factors_studies / Screening_studies Límite: Humans Idioma: En Revista: Med Sci Monit Asunto de la revista: MEDICINA Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos