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Glucopyranosylidene-spiro-imidazolinones, a New Ring System: Synthesis and Evaluation as Glycogen Phosphorylase Inhibitors by Enzyme Kinetics and X-ray Crystallography.
Szabó, Katalin E; Kyriakis, Efthimios; Psarra, Anna-Maria G; Karra, Aikaterini G; Sipos, Ádám; Docsa, Tibor; Stravodimos, George A; Katsidou, Elisabeth; Skamnaki, Vassiliki T; Liggri, Panagiota G V; Zographos, Spyros E; Mándi, Attila; Király, Sándor Balázs; Kurtán, Tibor; Leonidas, Demetres D; Somsák, László.
Afiliación
  • Szabó KE; Department of Organic Chemistry , University of Debrecen , P.O. Box 400, H-4002 Debrecen , Hungary.
  • Kyriakis E; Department of Biochemistry and Biotechnology , University of Thessaly, Biopolis , 41500 Larissa , Greece.
  • Psarra AG; Department of Biochemistry and Biotechnology , University of Thessaly, Biopolis , 41500 Larissa , Greece.
  • Karra AG; Department of Biochemistry and Biotechnology , University of Thessaly, Biopolis , 41500 Larissa , Greece.
  • Sipos Á; Department of Medical Chemistry, Faculty of Medicine , University of Debrecen , Egyetem tér 1 , H-4032 Debrecen , Hungary.
  • Docsa T; Department of Medical Chemistry, Faculty of Medicine , University of Debrecen , Egyetem tér 1 , H-4032 Debrecen , Hungary.
  • Stravodimos GA; Department of Biochemistry and Biotechnology , University of Thessaly, Biopolis , 41500 Larissa , Greece.
  • Katsidou E; Department of Biochemistry and Biotechnology , University of Thessaly, Biopolis , 41500 Larissa , Greece.
  • Skamnaki VT; Department of Biochemistry and Biotechnology , University of Thessaly, Biopolis , 41500 Larissa , Greece.
  • Liggri PGV; Department of Biochemistry and Biotechnology , University of Thessaly, Biopolis , 41500 Larissa , Greece.
  • Zographos SE; Institute of Biology, Pharmaceutical Chemistry and Biotechnology , National Hellenic Research Foundation , 48 Vassileos Constantinou Avenue , 11635 Athens , Greece.
  • Mándi A; Institute of Biology, Pharmaceutical Chemistry and Biotechnology , National Hellenic Research Foundation , 48 Vassileos Constantinou Avenue , 11635 Athens , Greece.
  • Király SB; Department of Organic Chemistry , University of Debrecen , P.O. Box 400, H-4002 Debrecen , Hungary.
  • Kurtán T; Department of Organic Chemistry , University of Debrecen , P.O. Box 400, H-4002 Debrecen , Hungary.
  • Leonidas DD; Department of Organic Chemistry , University of Debrecen , P.O. Box 400, H-4002 Debrecen , Hungary.
  • Somsák L; Department of Biochemistry and Biotechnology , University of Thessaly, Biopolis , 41500 Larissa , Greece.
J Med Chem ; 62(13): 6116-6136, 2019 07 11.
Article en En | MEDLINE | ID: mdl-31251604
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Compuestos de Espiro / Glucógeno Fosforilasa / Imidazolinas / Inhibidores Enzimáticos / Glucósidos Límite: Animals / Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2019 Tipo del documento: Article País de afiliación: Hungria Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Compuestos de Espiro / Glucógeno Fosforilasa / Imidazolinas / Inhibidores Enzimáticos / Glucósidos Límite: Animals / Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2019 Tipo del documento: Article País de afiliación: Hungria Pais de publicación: Estados Unidos