Your browser doesn't support javascript.
loading
HemOnc: A new standard vocabulary for chemotherapy regimen representation in the OMOP common data model.
Warner, Jeremy L; Dymshyts, Dmitry; Reich, Christian G; Gurley, Michael J; Hochheiser, Harry; Moldwin, Zachary H; Belenkaya, Rimma; Williams, Andrew E; Yang, Peter C.
Afiliación
  • Warner JL; Vanderbilt University Medical Center, Nashville, TN, United States; HemOnc.org, LLC, Lexington, MA, United States. Electronic address: jeremy.warner@vumc.org.
  • Dymshyts D; Odysseus Data Services, Inc., Cambridge, MA, United States.
  • Reich CG; IQVIA, Cambridge, MA, United States.
  • Gurley MJ; Northwestern University, Chicago, IL, United States.
  • Hochheiser H; University of Pittsburgh, Pittsburgh, PA, United States.
  • Moldwin ZH; University of Illinois at Chicago College of Pharmacy, Chicago, IL, United States.
  • Belenkaya R; Memorial Sloan Kettering Cancer Center, New York, NY, United States.
  • Williams AE; Tufts University, Medford, MA, United States.
  • Yang PC; HemOnc.org, LLC, Lexington, MA, United States; Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
J Biomed Inform ; 96: 103239, 2019 08.
Article en En | MEDLINE | ID: mdl-31238109
Systematic application of observational data to the understanding of impacts of cancer treatments requires detailed information models allowing meaningful comparisons between treatment regimens. Unfortunately, details of systemic therapies are scarce in registries and data warehouses, primarily due to the complex nature of the protocols and a lack of standardization. Since 2011, we have been creating a curated and semi-structured website of chemotherapy regimens, HemOnc.org. In coordination with the Observational Health Data Sciences and Informatics (OHDSI) Oncology Subgroup, we have transformed a substantial subset of this content into the OMOP common data model, with bindings to multiple external vocabularies, e.g., RxNorm and the National Cancer Institute Thesaurus. Currently, there are >73,000 concepts and >177,000 relationships in the full vocabulary. Content related to the definition and composition of chemotherapy regimens has been released within the ATHENA tool (athena.ohdsi.org) for widespread utilization by the OHDSI membership. Here, we describe the rationale, data model, and initial contents of the HemOnc vocabulary along with several use cases for which it may be valuable.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Informática Médica / Hematología / Oncología Médica / Neoplasias / Antineoplásicos Tipo de estudio: Guideline / Prognostic_studies Límite: Humans País/Región como asunto: America do norte Idioma: En Revista: J Biomed Inform Asunto de la revista: INFORMATICA MEDICA Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Informática Médica / Hematología / Oncología Médica / Neoplasias / Antineoplásicos Tipo de estudio: Guideline / Prognostic_studies Límite: Humans País/Región como asunto: America do norte Idioma: En Revista: J Biomed Inform Asunto de la revista: INFORMATICA MEDICA Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos