New keys for old locks: carborane-containing drugs as platforms for mechanism-based therapies.
Chem Soc Rev
; 48(13): 3497-3512, 2019 Jul 01.
Article
en En
| MEDLINE
| ID: mdl-31214680
Icosahedral carboranes in medicine are still an emerging class of compounds with potential beneficial applications in drug design. These highly hydrophobic clusters are potential "new keys for old locks" which open up an exciting field of research for well-known, but challenging important therapeutic substrates, as demonstrated by the numerous examples discussed in this review.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Boranos
Tipo de estudio:
Prognostic_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Chem Soc Rev
Año:
2019
Tipo del documento:
Article
Pais de publicación:
Reino Unido