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The Effectiveness of Lumbar Drainage in the Management of Delayed or Recurrent Cerebrospinal Fluid Leaks: A Retrospective Case Series in a Single Center.
Fan, ShuangMin; Chen, YaXin; Cao, Yi; Liu, LunXin; Liu, FuJun; Zhang, ChangWei; Zhou, LiangXue.
Afiliación
  • Fan S; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan Province, P.R. China.
  • Chen Y; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan Province, P.R. China.
  • Cao Y; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan Province, P.R. China.
  • Liu L; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan Province, P.R. China.
  • Liu F; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan Province, P.R. China.
  • Zhang C; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan Province, P.R. China.
  • Zhou L; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan Province, P.R. China. Electronic address: zhlxlll@163.com.
World Neurosurg ; 129: e845-e850, 2019 Sep.
Article en En | MEDLINE | ID: mdl-31212030
OBJECTIVE: Little is known about the effectiveness of lumbar drainage (LD) in the treatment of delayed or recurrent cerebrospinal fluid (CSF) leaks. We report our institutional experience and the effectiveness of LD in the management of delayed or recurrent CSF leaks. METHODS: Between January 2014 and December 2018, a total 21 patients with delayed or recurrent CSF leaks were enrolled in the research. All patients were treated conservatively for 48 hours, and LD was prescribed if CSF leaks still existed after 48 hours. If LD failed, endoscopic endonasal surgery (EES) was performed as soon as possible. Medical records were collected to analyze the effectiveness of LD. RESULTS: Among 21 patients, 4 patients experienced resolution with conservative treatment, and 17 patients were treated by CSF diversion by LD. The total cure rate of LD was 9/17 (52.9%). The cure rate was not statistically significantly different (relative risk = 3.33; Fisher exact test P = 0.131) between the traumatic group (8/12, 66.7%) and the transsphenoidal surgery group (1/5, 20.0%). During the follow-up time, no recurrence of CSF leaks was observed. CONCLUSIONS: The cure rate of LD in delayed or recurrent CSF leaks was lower than that of initial treatment with LD. The cure rate in the traumatic group tended to be higher than that in the transsphenoidal surgery group. EES can be used as a remedial treatment for patients in whom LD has failed.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Derivaciones del Líquido Cefalorraquídeo / Resultado del Tratamiento / Neuroendoscopía / Espera Vigilante / Pérdida de Líquido Cefalorraquídeo Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Límite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: World Neurosurg Asunto de la revista: NEUROCIRURGIA Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Derivaciones del Líquido Cefalorraquídeo / Resultado del Tratamiento / Neuroendoscopía / Espera Vigilante / Pérdida de Líquido Cefalorraquídeo Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Límite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: World Neurosurg Asunto de la revista: NEUROCIRURGIA Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos