A role for kinesin-1 subunits KIF5B/KLC1 in regulating epithelial mesenchymal plasticity in breast tumorigenesis.

Moamer, Alaa; Hachim, Ibrahim Y; Binothman, Najat; Wang, Ni; Lebrun, Jean-Jacques; Ali, Suhad

Moamer, Alaa; Hachim, Ibrahim Y; Binothman, Najat; Wang, Ni; Lebrun, Jean-Jacques; Ali, Suhad.

Afiliación

Moamer A; Department of Medicine, Cancer Research Program, Centre for Translational Biology, McGill University Health Centre, McGill University, Canada. Electronic address: alaa.moamer@mail.mcgill.ca.
Hachim IY; Department of Medicine, Cancer Research Program, Centre for Translational Biology, McGill University Health Centre, McGill University, Canada. Electronic address: ibrahim.hachim@mail.mcgill.ca.
Binothman N; Department of Medicine, Cancer Research Program, Centre for Translational Biology, McGill University Health Centre, McGill University, Canada. Electronic address: najat.binothman@mail.mcgill.ca.
Wang N; Department of Medicine, Cancer Research Program, Centre for Translational Biology, McGill University Health Centre, McGill University, Canada. Electronic address: ni.wang79@gmail.com.
Lebrun JJ; Department of Medicine, Cancer Research Program, Centre for Translational Biology, McGill University Health Centre, McGill University, Canada. Electronic address: jj.lebrun@mcgill.ca.
Ali S; Department of Medicine, Cancer Research Program, Centre for Translational Biology, McGill University Health Centre, McGill University, Canada. Electronic address: suhad.ali@mcgill.ca.

EBioMedicine ; 45: 92-107, 2019 Jul.

Article en En | MEDLINE | ID: mdl-31204277

Asunto(s)

Neoplasias de la Mama/genética; Carcinogénesis/genética; Transición Epitelial-Mesenquimal/genética; Cinesinas/genética; Proteínas Asociadas a Microtúbulos/genética; Animales; Neoplasias de la Mama/patología; Línea Celular Tumoral; Proliferación Celular/genética; Femenino; Regulación Neoplásica de la Expresión Génica/genética; Xenoinjertos; Humanos; Ratones; Prolactina/genética; Factor de Crecimiento Transformador beta/genética

Palabras clave

Cancer stem cells; Differentiation; EMT; Epithelial mesenchymal plasticity; Invasion; KIF5B; KLC1; Prolactin; TGFß; Xenograft

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Cinesinas / Transición Epitelial-Mesenquimal / Carcinogénesis / Proteínas Asociadas a Microtúbulos Límite: Animals / Female / Humans Idioma: En Revista: EBioMedicine Año: 2019 Tipo del documento: Article Pais de publicación: Países Bajos

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