Exposure to polybrominated biphenyl and stochastic epigenetic mutations: application of a novel epigenetic approach to environmental exposure in the Michigan polybrominated biphenyl registry.

Curtis, Sarah W; Cobb, Dawayland O; Kilaru, Varun; Terrell, Metrecia L; Marder, M Elizabeth; Barr, Dana Boyd; Marsit, Carmen J; Marcus, Michele; Conneely, Karen N; Smith, Alicia K

Curtis, Sarah W; Cobb, Dawayland O; Kilaru, Varun; Terrell, Metrecia L; Marder, M Elizabeth; Barr, Dana Boyd; Marsit, Carmen J; Marcus, Michele; Conneely, Karen N; Smith, Alicia K.

Afiliación

Curtis SW; a Genetics and Molecular Biology Program, Laney Graduate School, Emory University School of Medicine , Atlanta , GA , USA.
Cobb DO; b Department of Gynecology and Obstetrics, Emory University School of Medicine , Atlanta , GA , USA.
Kilaru V; b Department of Gynecology and Obstetrics, Emory University School of Medicine , Atlanta , GA , USA.
Terrell ML; c Department of Epidemiology, Emory University Rollins School of Public Health , Atlanta , GA , USA.
Marder ME; d Department of Environmental Health, Emory University Rollins School of Public Health , Atlanta , GA , USA.
Barr DB; d Department of Environmental Health, Emory University Rollins School of Public Health , Atlanta , GA , USA.
Marsit CJ; d Department of Environmental Health, Emory University Rollins School of Public Health , Atlanta , GA , USA.
Marcus M; e Departments of Epidemiology, Environmental Health, Emory University Rollins School of Public Health, and Department of Pediatrics Emory University School of Medicine , Atlanta , GA , USA.
Conneely KN; f Department of Human Genetics, Emory University School of Medicine , Atlanta , GA , USA.
Smith AK; g Departments of Gynecology and Obstetrics & Psychiatry and Behavioral Science, Emory University School of Medicine , Atlanta , GA , USA.

Epigenetics ; 14(10): 1003-1018, 2019 10.

Article en En | MEDLINE | ID: mdl-31200609

Asunto(s)

Metilación de ADN/efectos de los fármacos; Mutación; Bifenilos Polibrominados/efectos adversos; Secuenciación Completa del Genoma/métodos; Adulto; Factores de Edad; Anciano; Estudios de Cohortes; Exposición a Riesgos Ambientales/efectos adversos; Epigénesis Genética/efectos de los fármacos; Femenino; Estudio de Asociación del Genoma Completo; Humanos; Modelos Lineales; Masculino; Michigan; Persona de Mediana Edad

Palabras clave

DNA methylation; Endocrine-disrupting compound; PBB; SEM; brominated flame retardant; environmental health; epigenetics; epimutations; interpersonal variation; polybrominated biphenyl

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bifenilos Polibrominados / Metilación de ADN / Secuenciación Completa del Genoma / Mutación Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: America do norte Idioma: En Revista: Epigenetics Asunto de la revista: GENETICA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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