Accurately cleavable goat ß-lactoglobulin signal peptide efficiently guided translation of a recombinant human plasminogen activator in transgenic rabbit mammary gland.

Lu, Rui; Zhang, Ting; Song, Shaozheng; Zhou, Minya; Jiang, Lei; He, Zhengyi; Yuan, Yuguo; Yuan, Tingting; Lu, Yaoyao; Yan, Kunning; Cheng, Yong

Lu, Rui; Zhang, Ting; Song, Shaozheng; Zhou, Minya; Jiang, Lei; He, Zhengyi; Yuan, Yuguo; Yuan, Tingting; Lu, Yaoyao; Yan, Kunning; Cheng, Yong.

Afiliación

Lu R; College of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Zhang T; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, China.
Song S; College of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Zhou M; School of Nursing, Wuxi Taihu University, Wuxi, China.
Jiang L; College of Veterinary Medicine, Yangzhou University, Yangzhou, China.
He Z; College of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Yuan Y; College of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Yuan T; College of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Lu Y; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, China.
Yan K; Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, China.
Cheng Y; Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, China.

Biosci Rep ; 39(6)2019 06 28.

Article en En | MEDLINE | ID: mdl-31196965

Asunto(s)

Animales Modificados Genéticamente/genética; Lactoglobulinas/genética; Glándulas Mamarias Animales/metabolismo; Activadores Plasminogénicos/genética; Señales de Clasificación de Proteína/genética; Conejos/genética; Animales; Femenino; Cabras/genética; Humanos; Biosíntesis de Proteínas; Proteínas Recombinantes/genética

Palabras clave

BLG; mammary gland bioreactor; purification; rabbit; rhPA; signal peptide

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Conejos / Señales de Clasificación de Proteína / Animales Modificados Genéticamente / Activadores Plasminogénicos / Lactoglobulinas / Glándulas Mamarias Animales Límite: Animals / Female / Humans Idioma: En Revista: Biosci Rep Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

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