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All Ion Differential Analysis Refines the Detection of Terminal and Internal Diagnostic Fragment Ions for the Characterization of Biologics Product-Related Variants and Impurities by Middle-down Mass Spectrometry.
Griaud, François; Denefeld, Blandine; Kao-Scharf, Chi-Ya; Dayer, Jérôme; Lang, Manuel; Chen, Jian-You; Berg, Matthias.
Afiliación
  • Griaud F; Analytical Development and Characterization, Biopharmaceutical Product and Process Development, Technical Research and Development , Novartis Pharma AG , WKL693.3.20 , Postfach, CH-4002 , Basel , Switzerland.
  • Denefeld B; Analytical Development and Characterization, Biopharmaceutical Product and Process Development, Technical Research and Development , Novartis Pharma AG , WKL693.3.20 , Postfach, CH-4002 , Basel , Switzerland.
  • Kao-Scharf CY; Analytical Development and Characterization, Biopharmaceutical Product and Process Development, Technical Research and Development , Novartis Pharma AG , WKL693.3.20 , Postfach, CH-4002 , Basel , Switzerland.
  • Dayer J; Analytical Development and Characterization, Biopharmaceutical Product and Process Development, Technical Research and Development , Novartis Pharma AG , WKL693.3.20 , Postfach, CH-4002 , Basel , Switzerland.
  • Lang M; Analytical Development and Characterization, Biopharmaceutical Product and Process Development, Technical Research and Development , Novartis Pharma AG , WKL693.3.20 , Postfach, CH-4002 , Basel , Switzerland.
  • Chen JY; Analytical Development and Characterization, Biopharmaceutical Product and Process Development, Technical Research and Development , Novartis Pharma AG , WKL693.3.20 , Postfach, CH-4002 , Basel , Switzerland.
  • Berg M; Analytical Development and Characterization, Biopharmaceutical Product and Process Development, Technical Research and Development , Novartis Pharma AG , WKL693.3.20 , Postfach, CH-4002 , Basel , Switzerland.
Anal Chem ; 91(14): 8845-8852, 2019 07 16.
Article en En | MEDLINE | ID: mdl-31187983
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inmunoglobulina G / Anticuerpos Monoclonales Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Anal Chem Año: 2019 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inmunoglobulina G / Anticuerpos Monoclonales Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Anal Chem Año: 2019 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Estados Unidos