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CD45RA+CCR7- CD8 T cells lacking co-stimulatory receptors demonstrate enhanced frequency in peripheral blood of NSCLC patients responding to nivolumab.
Kunert, Andre; Basak, Edwin A; Hurkmans, Daan P; Balcioglu, Hayri E; Klaver, Yarne; van Brakel, Mandy; Oostvogels, Astrid A M; Lamers, Cor H J; Bins, Sander; Koolen, Stijn L W; van der Veldt, Astrid A M; Sleijfer, Stefan; Mathijssen, Ron H J; Aerts, Joachim G J V; Debets, Reno.
Afiliación
  • Kunert A; Laboratory of Tumor Immunology, Department of Medical Oncology, Erasmus MC Cancer Institute, Office Be 430b, Wytemaweg 80, 3015, CN, Rotterdam, The Netherlands. a.kunert@kitepharma.com.
  • Basak EA; Department of Pulmonary Diseases, Erasmus MC Cancer Institute, Rotterdam, The Netherlands. a.kunert@kitepharma.com.
  • Hurkmans DP; Laboratory of Translational Pharmacology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
  • Balcioglu HE; Laboratory of Translational Pharmacology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
  • Klaver Y; Laboratory of Tumor Immunology, Department of Medical Oncology, Erasmus MC Cancer Institute, Office Be 430b, Wytemaweg 80, 3015, CN, Rotterdam, The Netherlands.
  • van Brakel M; Laboratory of Tumor Immunology, Department of Medical Oncology, Erasmus MC Cancer Institute, Office Be 430b, Wytemaweg 80, 3015, CN, Rotterdam, The Netherlands.
  • Oostvogels AAM; Laboratory of Tumor Immunology, Department of Medical Oncology, Erasmus MC Cancer Institute, Office Be 430b, Wytemaweg 80, 3015, CN, Rotterdam, The Netherlands.
  • Lamers CHJ; Laboratory of Tumor Immunology, Department of Medical Oncology, Erasmus MC Cancer Institute, Office Be 430b, Wytemaweg 80, 3015, CN, Rotterdam, The Netherlands.
  • Bins S; Laboratory of Tumor Immunology, Department of Medical Oncology, Erasmus MC Cancer Institute, Office Be 430b, Wytemaweg 80, 3015, CN, Rotterdam, The Netherlands.
  • Koolen SLW; Laboratory of Translational Pharmacology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
  • van der Veldt AAM; Laboratory of Translational Pharmacology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
  • Sleijfer S; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
  • Mathijssen RHJ; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
  • Aerts JGJV; Laboratory of Translational Pharmacology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
  • Debets R; Department of Pulmonary Diseases, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
J Immunother Cancer ; 7(1): 149, 2019 06 08.
Article en En | MEDLINE | ID: mdl-31176366
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antígenos Comunes de Leucocito / Antígenos CD28 / Carcinoma de Pulmón de Células no Pequeñas / Linfocitos T CD8-positivos / Receptores CCR7 / Nivolumab / Neoplasias Pulmonares Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Immunother Cancer Año: 2019 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antígenos Comunes de Leucocito / Antígenos CD28 / Carcinoma de Pulmón de Células no Pequeñas / Linfocitos T CD8-positivos / Receptores CCR7 / Nivolumab / Neoplasias Pulmonares Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Immunother Cancer Año: 2019 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Reino Unido