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Ta2O5/rGO Nanocomposite Modified Electrodes for Detection of Tryptophan through Electrochemical Route.
Zhou, Shun; Deng, Zefeng; Wu, Zhongkang; Xie, Mei; Tian, Yaling; Wu, Yiyong; Liu, Jun; Li, Guangli; He, Quanguo.
Afiliación
  • Zhou S; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, School of Life Science and Chemistry, Hunan University of Technology, Zhuzhou 412007, China. zs1187357805@163.com.
  • Deng Z; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, School of Life Science and Chemistry, Hunan University of Technology, Zhuzhou 412007, China. dzf18073872860@163.com.
  • Wu Z; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, School of Life Science and Chemistry, Hunan University of Technology, Zhuzhou 412007, China. wzk18897496745@163.com.
  • Xie M; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, School of Life Science and Chemistry, Hunan University of Technology, Zhuzhou 412007, China. meixie1015@126.com.
  • Tian Y; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, School of Life Science and Chemistry, Hunan University of Technology, Zhuzhou 412007, China. tianyaling0212@163.com.
  • Wu Y; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, School of Life Science and Chemistry, Hunan University of Technology, Zhuzhou 412007, China. wyy5082010@163.com.
  • Liu J; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, School of Life Science and Chemistry, Hunan University of Technology, Zhuzhou 412007, China. junliu@hut.edu.cn.
  • Li G; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, School of Life Science and Chemistry, Hunan University of Technology, Zhuzhou 412007, China. guangli010@hut.edu.cn.
  • He Q; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, School of Life Science and Chemistry, Hunan University of Technology, Zhuzhou 412007, China. hequanguo@hut.edu.cn.
Nanomaterials (Basel) ; 9(6)2019 May 28.
Article en En | MEDLINE | ID: mdl-31142057
l-tryptophan is one of the eight kinds of essential amino acids for sustainable human life activity. It is common to detect the concentration of tryptophan in human serum for diagnosing and preventing brain related diseases. Herein, in this study, GCE (glassy carbon electrode) modified by Ta2O5-reduced graphene oxide (-rGO) composite (Ta2O5-rGO-GCE) is synthesized by the hydrothermal synthesis-calcination methods, which is used for detecting the concentration of tryptophan in human serum under the as-obtained optimal detection conditions. As a result, the obtained Ta2O5-rGO-GCE shows larger electrochemical activity area than other bare GCE and rGO-GCE due to the synergistic effect of Ta2O5 NPs and rGO. Meanwhile, Ta2O5-rGO-GCE shows an excellent response to tryptophan during the oxidation process in 0.1 M phosphate buffer solution (pH = 6). Moreover, three wide linear detection range (1.0-8.0 µM, 8.0-80 µM and 80-800 µM) and a low limit of detection (LOD) of 0.84 µM (S/N = 3) in the detection of tryptophan are also presented, showing the larger linear ranges and lower detection limit by employing Ta2O5-rGO-GCE. Finally, the as-proposed Ta2O5-rGO-GCE with satisfactory recoveries (101~106%) is successfully realized for the detection of tryptophan in human serum. The synthesis of Ta2O5-rGO-GCE in this article could provide a slight view for the synthesis of other electrochemical catalytic systems in detection of trace substance in human serum.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies Idioma: En Revista: Nanomaterials (Basel) Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies Idioma: En Revista: Nanomaterials (Basel) Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza