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Hourly Effect of Pretreatment With IV Antibiotics on Blood Culture Positivity Rate in Emergency Department Patients.
Rand, Kenneth H; Beal, Stacy G; Rivera, Kimberly; Allen, Brandon; Payton, Thomas; Lipori, Gloria P.
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  • Rand KH; Department of Pathology, Immunology and Laboratory Medicine, Gainesville, Florida.
  • Beal SG; Department of Pathology, Immunology and Laboratory Medicine, Gainesville, Florida.
  • Rivera K; Department of Emergency Medicine, UFHealth Shands Hospital, University of Florida, Gainesville, Florida.
  • Allen B; Department of Emergency Medicine, UFHealth Shands Hospital, University of Florida, Gainesville, Florida.
  • Payton T; Department of Emergency Medicine, UFHealth Shands Hospital, University of Florida, Gainesville, Florida.
  • Lipori GP; Office of Chief Information Officer, UFHealth Shands Hospital, University of Florida, Gainesville, Florida.
Open Forum Infect Dis ; 6(5): ofz179, 2019 May.
Article en En | MEDLINE | ID: mdl-31139670
Although it is intuitive that antibiotics administered before obtaining a blood culture would reduce the likelihood of obtaining a positive culture, it is not clear exactly how rapidly and to what extent blood becomes sterile after administration of intravenous (IV) antibiotics. Using a large data set of patients admitted from the UFHealth Shands Adult Emergency Department (ED) between 2012 and 2016 (n = 25 686), we had the opportunity to more closely examine the effect of starting IV antibiotics before vs after obtaining blood cultures. We present data on the effect of pretreatment with IV antibiotics for both septic and nonseptic ED patients on the blood culture positivity rate on an hour-by-hour basis, as well as the effects on distribution of species recovered and the impact of antibiotic resistance in empiric treatment with antibiotics.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Open Forum Infect Dis Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Open Forum Infect Dis Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos