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Endothelial dysfunction in patients with ankylosing spondylitis.
Losinska, Katarzyna; Korkosz, Mariusz; Kwasny-Krochin, Beata.
Afiliación
  • Losinska K; Division of Rheumatology, University Hospital, Cracow, Poland.
  • Korkosz M; Department of Rheumatology, Jagiellonian University Medical College, Cracow, Poland.
  • Kwasny-Krochin B; Department of Rheumatology, Jagiellonian University Medical College, Cracow, Poland.
Reumatologia ; 57(2): 100-105, 2019.
Article en En | MEDLINE | ID: mdl-31130748
Ankylosing spondylitis (AS) is associated with accelerated atherosclerosis and enhanced cardiovascular morbidity and mortality compared to the general population. The mechanisms and mediators of this phenomenon have not been fully explained, but an expanding body of evidence demonstrates that increased cardiovascular risk in AS is heralded by endothelial dysfunction. We performed a literature review using the PubMed database from the year 2006 up to 2018. In this article we review the epidemiology, current evidence for impaired endothelial function, potential mechanisms and markers controlling this dysfunction, and finally we summarize the data regarding the efficacy of pharmacotherapy in reducing endothelial dysfunction in patients suffering from AS.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Reumatologia Año: 2019 Tipo del documento: Article País de afiliación: Polonia Pais de publicación: Polonia
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Reumatologia Año: 2019 Tipo del documento: Article País de afiliación: Polonia Pais de publicación: Polonia