Your browser doesn't support javascript.
loading
Iron-Catalyzed Regioselective α-C-H Alkylation of N-Methylanilines: Cross-Dehydrogenative Coupling between Unactivated C(sp3)-H and C(sp3)-H Bonds via a Radical Process.
Li, Ze-Lin; Sun, Kang-Kang; Wu, Peng-Yu; Cai, Chun.
Afiliación
  • Li ZL; Chemical Engineering College , Nanjing University of Science and Technology , Nanjing 210094 , People's Republic of China.
  • Sun KK; Chemical Engineering College , Nanjing University of Science and Technology , Nanjing 210094 , People's Republic of China.
  • Wu PY; Chemical Engineering College , Nanjing University of Science and Technology , Nanjing 210094 , People's Republic of China.
  • Cai C; Chemical Engineering College , Nanjing University of Science and Technology , Nanjing 210094 , People's Republic of China.
J Org Chem ; 84(11): 6830-6839, 2019 Jun 07.
Article en En | MEDLINE | ID: mdl-31117558
The iron-catalyzed α-C-H alkylation of N-methylanilines without any directing group by cross-dehydrogenative coupling between unactivated C(sp3)-H and C(sp3)-H bonds has been established for the first time, which provides a good complement to C(sp3)-H activation reactions and expands the field of Fe-catalyzed C-H functionalizations. Many different C(sp3)-H bonds in cyclic alkanes, cyclic ethers, and toluene derivatives can be used as coupling partners. Mechanistic investigations including the radical reaction process, the main role of various reagents, and the kinetic isotope effect experiment were also described.
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Org Chem Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Org Chem Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos