An Improved Method for the Synthesis of Butein Using SOCl<sub>2</sub>/EtOH as Catalyst and Deciphering Its Inhibition Mechanism on Xanthine Oxidase.

Hou, Yu-Xue; Sun, Shi-Wei; Liu, Yang; Li, Yan; Liu, Xiao-Hong; Wang, Wei; Zhang, Shuang; Wang, Wei

An Improved Method for the Synthesis of Butein Using SOCl₂/EtOH as Catalyst and Deciphering Its Inhibition Mechanism on Xanthine Oxidase.

Hou, Yu-Xue; Sun, Shi-Wei; Liu, Yang; Li, Yan; Liu, Xiao-Hong; Wang, Wei; Zhang, Shuang; Wang, Wei.

Afiliación

Hou YX; Department of Natural Medicine and Pharmacognosy, School of Pharmacy, Qingdao University, Qingdao 260021, China. hyx19931008@163.com.
Sun SW; Department of Natural Medicine and Pharmacognosy, School of Pharmacy, Qingdao University, Qingdao 260021, China. sunsw@qdu.edu.cn.
Liu Y; Department of Natural Medicine and Pharmacognosy, School of Pharmacy, Qingdao University, Qingdao 260021, China. buckuper@163.com.
Li Y; Department of Natural Medicine and Pharmacognosy, School of Pharmacy, Qingdao University, Qingdao 260021, China. liyanyaohua@126.com.
Liu XH; Department of Natural Medicine and Pharmacognosy, School of Pharmacy, Qingdao University, Qingdao 260021, China. liuxiaohong1043@163.com.
Wang W; Department of Natural Medicine and Pharmacognosy, School of Pharmacy, Qingdao University, Qingdao 260021, China. justwangwade@126.com.
Zhang S; Department of Natural Medicine and Pharmacognosy, School of Pharmacy, Qingdao University, Qingdao 260021, China. qdeduzhangshuang@163.com.
Wang W; Department of Natural Medicine and Pharmacognosy, School of Pharmacy, Qingdao University, Qingdao 260021, China. w.w.wangwei@263.net.

Molecules ; 24(10)2019 May 21.

Article en En | MEDLINE | ID: mdl-31117192

Asunto(s)

Catálisis; Chalconas/síntesis química; Óxidos de Azufre/química; Xantina Oxidasa/química; Sitios de Unión; Dominio Catalítico; Chalconas/química; Etanol/química; Enlace de Hidrógeno; Interacciones Hidrofóbicas e Hidrofílicas; Cinética; Oxidación-Reducción; Conformación Proteica; Relación Estructura-Actividad; Xantina Oxidasa/antagonistas & inhibidores

Palabras clave

SOCl2/EtOH; butein; florescence spectroscopy; inhibitory mechanism; kinetic analysis; molecular docking; xanthine oxidase

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Óxidos de Azufre / Xantina Oxidasa / Catálisis / Chalconas Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza

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