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PEELING OF THE INTERNAL LIMITING MEMBRANE WITH FOVEAL SPARING FOR TREATMENT OF DEGENERATIVE LAMELLAR MACULAR HOLE.
Morescalchi, Francesco; Russo, Andrea; Gambicorti, Elena; Cancarini, Anna; Scaroni, Nicolò; Bahja, Hassan; Costagliola, Ciro; Semeraro, Francesco.
Afiliación
  • Morescalchi F; Department of Neurological and Vision Sciences, Eye Clinic, University of Brescia, Brescia, Italy; and.
  • Russo A; Department of Neurological and Vision Sciences, Eye Clinic, University of Brescia, Brescia, Italy; and.
  • Gambicorti E; Department of Neurological and Vision Sciences, Eye Clinic, University of Brescia, Brescia, Italy; and.
  • Cancarini A; Department of Neurological and Vision Sciences, Eye Clinic, University of Brescia, Brescia, Italy; and.
  • Scaroni N; Department of Neurological and Vision Sciences, Eye Clinic, University of Brescia, Brescia, Italy; and.
  • Bahja H; Department of Neurological and Vision Sciences, Eye Clinic, University of Brescia, Brescia, Italy; and.
  • Costagliola C; Department of Health Sciences, Eye Clinic, University of Molise, Campobasso, Italy.
  • Semeraro F; Department of Neurological and Vision Sciences, Eye Clinic, University of Brescia, Brescia, Italy; and.
Retina ; 40(6): 1087-1093, 2020 Jun.
Article en En | MEDLINE | ID: mdl-31107710
PURPOSE: To compare the functional and anatomical results of fovea-sparing internal limiting membrane peeling during vitrectomy with those of observation for degenerative lamellar macular hole with lamellar hole-associated epiretinal proliferation. DESIGN: A prospective, randomized, comparative pilot study. METHODS: Thirty-six eyes were randomized to undergo surgery with foveal internal limiting membrane sparing (Group S) or observation only (Group C). The main outcome measures were foveal retinal sensitivity, visual acuity, and central retinal thickness. RESULTS: After 6 months, a significant difference was found in foveal retinal sensitivity between Group S (12.8 ± 1.7 dB) and Group C (9.39 ± 1.8 dB; P < 0.001). Similarly, best-corrected visual acuity improved in Group S and remained stable in Group C (respectively, 0.17 ± 0.13 and 0.46 ± 0.21 logMAR; P < 0.001). A significant increase in central retinal thickness was observed in Group S, but not in Group C (272 ± 24 vs. 147 ± 20 µm, P < 0.001). CONCLUSION: Fovea-sparing internal limiting membrane peeling is a feasible treatment for degenerative lamellar macular hole with lamellar hole-associated epiretinal proliferation, yielding better improvements in best-corrected visual acuity and foveal retinal sensitivity than observation alone. Further studies are needed to optimize this new surgical approach.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Perforaciones de la Retina / Membrana Basal / Vitrectomía / Agudeza Visual / Tomografía de Coherencia Óptica / Fóvea Central Tipo de estudio: Clinical_trials / Diagnostic_studies / Observational_studies Límite: Aged / Female / Humans / Male Idioma: En Revista: Retina Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Perforaciones de la Retina / Membrana Basal / Vitrectomía / Agudeza Visual / Tomografía de Coherencia Óptica / Fóvea Central Tipo de estudio: Clinical_trials / Diagnostic_studies / Observational_studies Límite: Aged / Female / Humans / Male Idioma: En Revista: Retina Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos